y
Basic Information | |
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Species | Sorghum bicolor |
Cazyme ID | Sb03g044100.1 |
Family | GT47 |
Protein Properties | Length: 433 Molecular Weight: 48446.8 Isoelectric Point: 9.5613 |
Chromosome | Chromosome/Scaffold: 3 Start: 71313221 End: 71316756 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 60 | 370 | 0 |
PLRVFMYDLPARFHVAMMGADDGAGFPAWPPSAGGIRRQHSVEYWMMASLQDGAAGPDGGREAVRVRDPDAADAFFVPFFSSLSFNVHGRNMTDPDTEAD RLLQVEIVDILWKSKYWQRSAGRDHVIPMHHPNAFRFLRAMVNASILIVSDFGRYTKELASLRKDVVAPYVHVVDSFLDDDPPDPFEARHTLLFFRGRTV RKDEGKIRAKLGKVLKGKEGVRFEDSIATGDGIKISTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSSRIELPFEDEIDYSEFSLFFSVEEALR PDYLLNQLRQI |
Full Sequence |
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Protein Sequence Length: 433 Download |
MGAPSSRALA LGAAFLLLLV ALPSAFLYLT TSAAPAAATR ATLLNLKPFS ARCAPAAAAP 60 LRVFMYDLPA RFHVAMMGAD DGAGFPAWPP SAGGIRRQHS VEYWMMASLQ DGAAGPDGGR 120 EAVRVRDPDA ADAFFVPFFS SLSFNVHGRN MTDPDTEADR LLQVEIVDIL WKSKYWQRSA 180 GRDHVIPMHH PNAFRFLRAM VNASILIVSD FGRYTKELAS LRKDVVAPYV HVVDSFLDDD 240 PPDPFEARHT LLFFRGRTVR KDEGKIRAKL GKVLKGKEGV RFEDSIATGD GIKISTEGMR 300 SSKFCLHPAG DTPSSCRLFD AIVSHCVPVI VSSRIELPFE DEIDYSEFSL FFSVEEALRP 360 DYLLNQLRQI PKKKWVDMWS KLKNVSHHYE FQYPPRKGDA VNMIWRQVRH KIPAVNLAIH 420 RNRRLKIPDW WG* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-49 | 61 | 370 | 318 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EAY77012.1 | 0 | 32 | 432 | 31 | 416 | hypothetical protein OsI_04969 [Oryza sativa Indica Group] |
RefSeq | NP_001045226.1 | 0 | 32 | 432 | 31 | 437 | Os01g0921300 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001152546.1 | 0 | 1 | 432 | 1 | 427 | exostosin-like [Zea mays] |
RefSeq | NP_176908.2 | 0 | 9 | 431 | 13 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002456855.1 | 0 | 1 | 432 | 1 | 432 | hypothetical protein SORBIDRAFT_03g044100 [Sorghum bicolor] |