| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g044520.1 |
| Family | GT47 |
| Protein Properties | Length: 418 Molecular Weight: 46905.2 Isoelectric Point: 6.8939 |
| Chromosome | Chromosome/Scaffold: 3 Start: 71872997 End: 71876172 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 50 | 345 | 0 |
| RLKVYVYELPTKYNKKMVAKDSRCLSHMFAAEIFMHRFLLSSAIRTLNPEEADWFYTPVYTTCDLTPWGHPLPFKSPRIMRSAIQFISNRWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIERGVLPLLRRATLVQTFGQKDHVCLKEGSITIPPYAPPQKMKTHLVPPGTPRSIFVYFRGLFYDTANDPEGGYYARGA RASVWENFKNNPLFDISTDHPPTYYEDMQRAVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVAEDDVPKLDTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 418 Download |
| MGTGSARAMA AALAVLLLAC SGAVAVARAQ DTERIEGSAG DVLEDDPVGR LKVYVYELPT 60 KYNKKMVAKD SRCLSHMFAA EIFMHRFLLS SAIRTLNPEE ADWFYTPVYT TCDLTPWGHP 120 LPFKSPRIMR SAIQFISNRW PYWNRTEGAD HFFVVPHDFG ACFHYQEEKA IERGVLPLLR 180 RATLVQTFGQ KDHVCLKEGS ITIPPYAPPQ KMKTHLVPPG TPRSIFVYFR GLFYDTANDP 240 EGGYYARGAR ASVWENFKNN PLFDISTDHP PTYYEDMQRA VFCLCPLGWA PWSPRLVEAV 300 VFGCIPVIIA DDIVLPFADA IPWEEIGVFV AEDDVPKLDT ILTSIPMEVI LRKQRLLANP 360 SMKQAMLFPQ PAQPGDAFHQ ILNGLARKLP HGEDVFLKPG LKVLNWTEGP RGDLKPW* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-84 | 50 | 345 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG31432.1 | 0 | 2 | 417 | 4 | 419 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
| RefSeq | NP_001045263.1 | 0 | 26 | 417 | 24 | 415 | Os01g0926600 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001130448.1 | 0 | 1 | 417 | 1 | 415 | hypothetical protein LOC100191546 [Zea mays] |
| RefSeq | NP_001142343.1 | 0 | 2 | 417 | 4 | 419 | hypothetical protein LOC100274514 [Zea mays] |
| RefSeq | XP_002459016.1 | 0 | 1 | 417 | 1 | 417 | hypothetical protein SORBIDRAFT_03g044520 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
