| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb03g044530.1 |
| Family | GT47 |
| Protein Properties | Length: 421 Molecular Weight: 47156.2 Isoelectric Point: 6.8974 |
| Chromosome | Chromosome/Scaffold: 3 Start: 71879497 End: 71882419 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 53 | 348 | 0 |
| RLKVYVYDLPSKYNKKLLKKDPRCLNHMFAAEIFMHRFLLSSAVRTFNPEEADWFYTPVYTTCDLTPSGLPLPFKSPRMMRSAIELIATNWPYWNRSEGA DHFFVTPHDFGACFHYQEEKAIGRGILPLLQRATLVQTFGQKNHVCLKDGSITIPPFAPPQKMQAHLIPADTPRSIFVYFRGLFYDTSNDPEGGYYARGA RASVWENFKNNPLFDISTDHPPTYYEDMQRSVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVAEEDVPKLDSILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 421 Download |
| MRRWVLAIAI LSAASAAALF LGAEAQAVQQ QGHQTERISG SAGDVLEDNP VGRLKVYVYD 60 LPSKYNKKLL KKDPRCLNHM FAAEIFMHRF LLSSAVRTFN PEEADWFYTP VYTTCDLTPS 120 GLPLPFKSPR MMRSAIELIA TNWPYWNRSE GADHFFVTPH DFGACFHYQE EKAIGRGILP 180 LLQRATLVQT FGQKNHVCLK DGSITIPPFA PPQKMQAHLI PADTPRSIFV YFRGLFYDTS 240 NDPEGGYYAR GARASVWENF KNNPLFDIST DHPPTYYEDM QRSVFCLCPL GWAPWSPRLV 300 EAVVFGCIPV IIADDIVLPF ADAIPWEEIG VFVAEEDVPK LDSILTSIPT DVILRKQRLL 360 ANPSMKQAML FPQPAQAGDA FHQILNGLAR KLPHGDNVFL KPGERVLNWT AGPPGDLKPW 420 * 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-88 | 53 | 348 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACF82849.1 | 0 | 29 | 420 | 26 | 418 | unknown [Zea mays] |
| GenBank | ACF86410.1 | 0 | 29 | 420 | 26 | 418 | unknown [Zea mays] |
| RefSeq | NP_001045264.1 | 0 | 30 | 420 | 27 | 417 | Os01g0926700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001149319.1 | 0 | 24 | 420 | 26 | 421 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
| RefSeq | XP_002459017.1 | 0 | 1 | 420 | 1 | 420 | hypothetical protein SORBIDRAFT_03g044530 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
