| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb04g008640.1 |
| Family | AA2 |
| Protein Properties | Length: 322 Molecular Weight: 35040.7 Isoelectric Point: 5.2092 |
| Chromosome | Chromosome/Scaffold: 4 Start: 10092237 End: 10094498 |
| Description | Peroxidase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA2 | 45 | 302 | 0 |
| QIIKAEVDRTLSVDRRMGASLLRLFFHDCFVQGCDASVLLDDDAAKSITSEKTAGPNDKSLRGFDVIDRIKDQVEAACGVPGARVGVVSCADILALVTKQ AVIYLAGQPGWAGWSLLLGRRDSTTANKDEANTVLPSPNSELPTLIEAFKNKNFTGRELVALSGAHTIGVAQCGNVDETQRQKCIDANNNNTFPLDDETP VDFDKGYYDNLLRDKGLLHSDRVLVDSNDLKLLVLQYARRKDLFFKDFANAMEKMSLM | |||
| Full Sequence |
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| Protein Sequence Length: 322 Download |
| MAASSSTTTT GGHYMFLVAL SLLSFAAYGQ LSEQFYAAKC PSLDQIIKAE VDRTLSVDRR 60 MGASLLRLFF HDCFVQGCDA SVLLDDDAAK SITSEKTAGP NDKSLRGFDV IDRIKDQVEA 120 ACGVPGARVG VVSCADILAL VTKQAVIYLA GQPGWAGWSL LLGRRDSTTA NKDEANTVLP 180 SPNSELPTLI EAFKNKNFTG RELVALSGAH TIGVAQCGNV DETQRQKCID ANNNNTFPLD 240 DETPVDFDKG YYDNLLRDKG LLHSDRVLVD SNDLKLLVLQ YARRKDLFFK DFANAMEKMS 300 LMSVLTGTNG EIRLNCSRVN Y* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00691 | ascorbate_peroxidase | 8.0e-15 | 37 | 300 | 285 | + Ascorbate peroxidases and cytochrome C peroxidases. Ascorbate peroxidases are a subgroup of heme-dependent peroxidases of the plant superfamily that share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Along with related catalase-peroxidases, ascorbate peroxidases belong to class I of the plant superfamily. Ascorbate peroxidases are found in the chloroplasts and/or cytosol of algae and plants, where they have been shown to control the concentration of lethal hydrogen peroxide molecules. The yeast cytochrome c peroxidase is a divergent member of the family; it forms a complex with cytochrome c to catalyze the reduction of hydrogen peroxide to water. | ||
| cd00314 | plant_peroxidase_like | 3.0e-28 | 45 | 300 | 283 | + Heme-dependent peroxidases similar to plant peroxidases. Along with animal peroxidases, these enzymes belong to a group of peroxidases containing a heme prosthetic group (ferriprotoporphyrin IX), which catalyzes a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. The plant peroxidase-like superfamily is found in all three kingdoms of life and carries out a variety of biosynthetic and degradative functions. Several sub-families can be identified. Class I includes intracellular peroxidases present in fungi, plants, archaea and bacteria, called catalase-peroxidases, that can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. Catalase-peroxidases are typically comprised of two homologous domains that probably arose via a single gene duplication event. Class II includes ligninase and other extracellular fungal peroxidases, while class III is comprised of classic extracellular plant peroxidases, like horseradish peroxidase. | ||
| PLN03030 | PLN03030 | 1.0e-50 | 35 | 320 | 313 | + cationic peroxidase; Provisional | ||
| pfam00141 | peroxidase | 1.0e-56 | 47 | 283 | 238 | + Peroxidase. | ||
| cd00693 | secretory_peroxidase | 7.0e-127 | 30 | 319 | 312 | + Horseradish peroxidase and related secretory plant peroxidases. Secretory peroxidases belong to class III of the plant heme-dependent peroxidase superfamily. All members of the superfamily share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Class III peroxidases are found in the extracellular space or in the vacuole in plants where they have been implicated in hydrogen peroxide detoxification, auxin catabolism and lignin biosynthesis, and stress response. Class III peroxidases contain four conserved disulphide bridges and two conserved calcium binding sites. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004601 | peroxidase activity |
| GO:0006979 | response to oxidative stress |
| GO:0020037 | heme binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABK23423.1 | 0 | 28 | 320 | 23 | 318 | unknown [Picea sitchensis] |
| Swiss-Prot | P22195 | 0 | 16 | 320 | 10 | 316 | PER1_ARAHY RecName: Full=Cationic peroxidase 1; AltName: Full=PNPC1; Flags: Precursor |
| RefSeq | XP_002266365.1 | 0 | 13 | 320 | 16 | 328 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002451849.1 | 0 | 1 | 321 | 1 | 321 | hypothetical protein SORBIDRAFT_04g008640 [Sorghum bicolor] |
| RefSeq | XP_002451850.1 | 0 | 6 | 320 | 2 | 323 | hypothetical protein SORBIDRAFT_04g008650 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1sch_B | 0 | 30 | 320 | 1 | 294 | A Chain A, Peanut Peroxidase |
| PDB | 1sch_A | 0 | 30 | 320 | 1 | 294 | A Chain A, Peanut Peroxidase |
| PDB | 1qo4_A | 0 | 30 | 320 | 2 | 304 | A Chain A, Peanut Peroxidase |
| PDB | 1pa2_A | 0 | 30 | 320 | 2 | 304 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 1qgj_B | 0 | 30 | 320 | 1 | 299 | A Chain A, Arabidopsis Thaliana Peroxidase N |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| betanidin degradation | RXN-8635 | EC-1.11.1.7 | peroxidase |
| Transmembrane Domains | |||||
|---|---|---|---|---|---|
| Start | End | ||||
| 12 | 29 | ||||
| Signal Peptide | |||||
|---|---|---|---|---|---|
| Cleavage Site | |||||
| 29 | |||||
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DR566244 | 299 | 28 | 311 | 0 |
| EW712044 | 306 | 30 | 320 | 0 |
| EX311888 | 294 | 28 | 306 | 0 |
| DR588285 | 290 | 46 | 320 | 0 |
| DR432298 | 310 | 28 | 320 | 0 |
| Orthologous Group | |||||
|---|---|---|---|---|---|
| Species | ID | ||||
| Aquilegia coerulea | Aquca_049_00044.1 | ||||
| Panicum virgatum | Pavirv00008965m | Pavirv00063819m | |||
| Setaria italica | Si017824m | ||||
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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