| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb06g024740.1 |
| Family | GT8 |
| Protein Properties | Length: 476 Molecular Weight: 53958.3 Isoelectric Point: 8.3502 |
| Chromosome | Chromosome/Scaffold: 6 Start: 53794006 End: 53798339 |
| Description | Nucleotide-diphospho-sugar transferases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT8 | 57 | 265 | 1.5e-27 |
| YEFYVATRVMMRSLRRLSADADRVVIASLDVPPLWVQALKDDGVKVVSVENLKNPYEKQENFNMRFKLTLNKLYAWSLISYERVVMLDSDNIFLQNTDEL FQCGQFCAVFINPCIFHTGLFVLQPSMDVFKNMLHELAVGRENPDGADQGFLASYFPDLLDQPMFHPPANGTKLQGTYRLPLGYQMDASYYYLKLRWSIP CGPNSVITF | |||
| Full Sequence |
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| Protein Sequence Length: 476 Download |
| MGWSAGLCWW LVAAVWVAAA AALVAAEGEV EVAVAVGAAP RRHAYASMMY MGTPRDYEFY 60 VATRVMMRSL RRLSADADRV VIASLDVPPL WVQALKDDGV KVVSVENLKN PYEKQENFNM 120 RFKLTLNKLY AWSLISYERV VMLDSDNIFL QNTDELFQCG QFCAVFINPC IFHTGLFVLQ 180 PSMDVFKNML HELAVGRENP DGADQGFLAS YFPDLLDQPM FHPPANGTKL QGTYRLPLGY 240 QMDASYYYLK LRWSIPCGPN SVITFPSAPW FKPWYWWSWP VLPLGLSWHE QRRENLGYSS 300 EIPVVLIQAV LYIGVIAVTR LARPSLSKMC YNRRMEKNTM FLLSLLRVVA AWSILAAYTI 360 PFFIIPRTVH PLLGWPLYLL GSFSLSSIVI NVFLLHPMTV LTTWFGFIGA LLVMAFPWYL 420 NGVVRALAVF AYAFCCAPLI WASLVKTMSS LHVLIERDAF RLGEPNQNAE FTKLY* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG5597 | COG5597 | 2.0e-5 | 53 | 214 | 179 | + Alpha-N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| PLN00176 | PLN00176 | 1.0e-7 | 68 | 214 | 185 | + galactinol synthase | ||
| cd06914 | GT8_GNT1 | 7.0e-8 | 45 | 274 | 251 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. | ||
| pfam01501 | Glyco_transf_8 | 8.0e-13 | 56 | 278 | 261 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
| cd02537 | GT8_Glycogenin | 2.0e-64 | 43 | 294 | 262 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAG90419.1 | 0 | 120 | 475 | 1 | 356 | unnamed protein product [Oryza sativa Japonica Group] |
| EMBL | CAH67416.1 | 0 | 40 | 475 | 39 | 474 | OSIGBa0143N19.10 [Oryza sativa (indica cultivar-group)] |
| GenBank | EEC77769.1 | 0 | 40 | 475 | 39 | 474 | hypothetical protein OsI_16920 [Oryza sativa Indica Group] |
| RefSeq | NP_001053509.1 | 0 | 48 | 475 | 1 | 428 | Os04g0553800 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002448294.1 | 0 | 40 | 475 | 40 | 475 | hypothetical protein SORBIDRAFT_06g024740 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1zct_B | 0.0000000000004 | 37 | 212 | 13 | 191 | A Chain A, Structure Of Glycogenin Truncated At Residue 270 In A Complex With Udp |
| PDB | 1zct_A | 0.0000000000004 | 37 | 212 | 13 | 191 | A Chain A, Structure Of Glycogenin Truncated At Residue 270 In A Complex With Udp |
| PDB | 3v8z_A | 0.0000000000004 | 37 | 212 | 13 | 191 | A Chain A, Structure Of Glycogenin Truncated At Residue 270 In A Complex With Udp |
| PDB | 3v8y_A | 0.0000000000004 | 37 | 212 | 13 | 191 | A Chain A, Structure Of Apo-Glycogenin Truncated At Residue 270 |
| PDB | 3usr_A | 0.0000000000004 | 37 | 212 | 13 | 191 | A Chain A, Structure Of Y194f Glycogenin Mutant Truncated At Residue 270 |
