| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb06g025200.1 |
| Family | GH29 |
| Protein Properties | Length: 514 Molecular Weight: 56471.1 Isoelectric Point: 5.5306 |
| Chromosome | Chromosome/Scaffold: 6 Start: 54181815 End: 54185357 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH29 | 36 | 334 | 0 |
| PSYAQLRWQLSEMALFLHFGPNTFTDSEWGTGRADPSVFAPSALDAGQWARVAAQGGFGRVVLTAKHHDGFCLWPSALTDYSVAASPWRGGAGDVVADLA AAARAEGIGLGLYLSPWDRHEPVYGDTIAYNEHYLGQMTELLTRYGDLEEIWLDGAKGDAKKMNYMFDAWFSLIHQLQQRVVIFSDAGPDTRWVGDEAGV AGYTCWSPFNKSSVTIGHTIAEYSRSGDPFGQDWVPAECDVSIRPGWFWHASEKPKNATTLLDIYYKSVGRNCLLILNVPPNSSGLIANEDILVLQEFT | |||
| Full Sequence |
|---|
| Protein Sequence Length: 514 Download |
| MAALLPLLLA HLLLCAHGAT ASSAATPPPL PVLPVPSYAQ LRWQLSEMAL FLHFGPNTFT 60 DSEWGTGRAD PSVFAPSALD AGQWARVAAQ GGFGRVVLTA KHHDGFCLWP SALTDYSVAA 120 SPWRGGAGDV VADLAAAARA EGIGLGLYLS PWDRHEPVYG DTIAYNEHYL GQMTELLTRY 180 GDLEEIWLDG AKGDAKKMNY MFDAWFSLIH QLQQRVVIFS DAGPDTRWVG DEAGVAGYTC 240 WSPFNKSSVT IGHTIAEYSR SGDPFGQDWV PAECDVSIRP GWFWHASEKP KNATTLLDIY 300 YKSVGRNCLL ILNVPPNSSG LIANEDILVL QEFTGIRHAI FSQNFAANAT VTANSVRGGQ 360 DNLQFAPSKV LEDGIYSYWA PQEGQTCWEM LFDLGRSTSF NMLQLQEPIQ LGQRVIEFHV 420 AILIDELWQT IVEGTTIGYK RLLLFPVVES RYLKLSIDSA RADPLISFFG VFMDPFSSRH 480 SLQNHVKPPR TNSSDVTMLR MAHASVNKSI AAM* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00812 | Alpha_L_fucos | 4.0e-22 | 74 | 333 | 281 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| pfam01120 | Alpha_L_fucos | 3.0e-23 | 74 | 333 | 274 | + Alpha-L-fucosidase. | ||
| COG3669 | COG3669 | 1.0e-55 | 40 | 472 | 446 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG47369.1 | 0 | 15 | 513 | 15 | 513 | alpha-L-fucosidase 1 precursor [Zea mays] |
| EMBL | CAH68057.1 | 0 | 16 | 513 | 20 | 517 | B0103C08-B0602B01.14 [Oryza sativa (indica cultivar-group)] |
| RefSeq | NP_001053546.1 | 0 | 16 | 513 | 20 | 517 | Os04g0560400 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001131532.1 | 0 | 15 | 513 | 15 | 513 | hypothetical protein LOC100192871 [Zea mays] |
| RefSeq | XP_002448322.1 | 0 | 1 | 513 | 1 | 513 | hypothetical protein SORBIDRAFT_06g025200 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ues_B | 0 | 36 | 467 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 36 | 467 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 36 | 467 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 36 | 467 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3uet_B | 0 | 36 | 467 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis D172aE217A MUTANT COMPLEXED WITH LACTO-N- Fucopentaose Ii |
