| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb06g030930.1 |
| Family | GH89 |
| Protein Properties | Length: 253 Molecular Weight: 29203.1 Isoelectric Point: 4.8812 |
| Chromosome | Chromosome/Scaffold: 6 Start: 59344668 End: 59347564 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH89 | 51 | 228 | 0 |
| YDLVDLTRQVLAKYANDVFLKIIESYKSNKMNQVTILCKHFLNLVNDLDTLLSSHEGFLLGPWLESAKGLARNSEQEIQYEWNARTQITMWFDNTETKAS LLRDYANKYWSGLLRDYYGPRAAIYFKHLLLSMEKNAPFALEEWRREWISLTNNWQSDRKVFSTTPTGDSLNISWSLY | |||
| Full Sequence |
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| Protein Sequence Length: 253 Download |
| MEGIEQNPIV YDLMSEMAFH HRQVDLQDKN RDVIVAFPDV EPFVIETPGL YDLVDLTRQV 60 LAKYANDVFL KIIESYKSNK MNQVTILCKH FLNLVNDLDT LLSSHEGFLL GPWLESAKGL 120 ARNSEQEIQY EWNARTQITM WFDNTETKAS LLRDYANKYW SGLLRDYYGP RAAIYFKHLL 180 LSMEKNAPFA LEEWRREWIS LTNNWQSDRK VFSTTPTGDS LNISWSLYIK YLSNTDPLEL 240 EGTGSPGKSA SL* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05089 | NAGLU | 3.0e-5 | 1 | 23 | 23 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| pfam12972 | NAGLU_C | 5.0e-68 | 51 | 231 | 181 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAE04506.2 | 0 | 1 | 242 | 480 | 817 | OSJNBb0059K02.16 [Oryza sativa (japonica cultivar-group)] |
| GenBank | EEC78143.1 | 0 | 1 | 242 | 480 | 817 | hypothetical protein OsI_17702 [Oryza sativa Indica Group] |
| GenBank | EEE61812.1 | 0 | 1 | 242 | 780 | 1117 | hypothetical protein OsJ_16433 [Oryza sativa Japonica Group] |
| RefSeq | NP_001054095.1 | 0 | 1 | 242 | 182 | 519 | Os04g0650900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002448659.1 | 0 | 1 | 252 | 1 | 252 | hypothetical protein SORBIDRAFT_06g030930 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4a4a_A | 5e-17 | 9 | 221 | 688 | 889 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vcc_A | 5e-17 | 9 | 221 | 665 | 866 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vcb_A | 5e-17 | 9 | 221 | 665 | 866 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vca_A | 5e-17 | 9 | 221 | 665 | 866 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vc9_A | 5e-17 | 9 | 221 | 665 | 866 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DT946530 | 204 | 51 | 253 | 0 |
| JG966546 | 203 | 51 | 253 | 0 |
| JG952105 | 203 | 51 | 253 | 0 |
| CA283788 | 173 | 51 | 223 | 0 |
| GT049437 | 270 | 28 | 243 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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