y
Basic Information | |
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Species | Sorghum bicolor |
Cazyme ID | Sb06g032380.1 |
Family | GT47 |
Protein Properties | Length: 457 Molecular Weight: 51940.7 Isoelectric Point: 9.3162 |
Chromosome | Chromosome/Scaffold: 6 Start: 60532587 End: 60535132 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 41 | 381 | 0 |
RRLRVYVADLPRALNYGLLDSYWSLRAADSRIEASSDPDHPPPNDHSPYPENPLIKQYSAEYWLLASLRAAATAAVRVVTDWREADVVFVPFFATLSAEM ELGWGTKGAFRKKDGNEDYRRQREVVDRVTSHPAWRRSGGRDHVFVMTDPVAMWHVRAEIAPAILLVVDFGGWYKVDSKSANRNSSRMIQHTQVSLLKDV IVPYTHLLPTLLLSENKDRPTLLYFKGAKHRHRGGLVREKLWDLLGNEPDVIMEEGFPNATGREQSIKGMQTSEFCLHPAGDTPTSCRLFDAIASLCIPV IVSDEVELPYEGMIDYTEFSIFVSVRNAMRPKWLTSYLRNI |
Full Sequence |
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Protein Sequence Length: 457 Download |
MKRLPVLAVP VLLLLVSLSF FLFRPTTPPV LSSRQAFEPD RRLRVYVADL PRALNYGLLD 60 SYWSLRAADS RIEASSDPDH PPPNDHSPYP ENPLIKQYSA EYWLLASLRA AATAAVRVVT 120 DWREADVVFV PFFATLSAEM ELGWGTKGAF RKKDGNEDYR RQREVVDRVT SHPAWRRSGG 180 RDHVFVMTDP VAMWHVRAEI APAILLVVDF GGWYKVDSKS ANRNSSRMIQ HTQVSLLKDV 240 IVPYTHLLPT LLLSENKDRP TLLYFKGAKH RHRGGLVREK LWDLLGNEPD VIMEEGFPNA 300 TGREQSIKGM QTSEFCLHPA GDTPTSCRLF DAIASLCIPV IVSDEVELPY EGMIDYTEFS 360 IFVSVRNAMR PKWLTSYLRN IPKQQKDEFR KNLARVQPIF EYNTSYSISR GSTSIDGAVS 420 HIWKKIHQKL PMIQEAIIRE KRKPDGASIP LRCHCT* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-63 | 39 | 381 | 355 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAE02830.1 | 0 | 24 | 456 | 23 | 464 | OSJNBa0043A12.35 [Oryza sativa (japonica cultivar-group)] |
GenBank | EEC78225.1 | 0 | 24 | 456 | 23 | 452 | hypothetical protein OsI_17865 [Oryza sativa Indica Group] |
RefSeq | NP_001137073.1 | 0 | 24 | 456 | 24 | 458 | hypothetical protein LOC100217246 [Zea mays] |
RefSeq | XP_002448739.1 | 0 | 24 | 456 | 24 | 456 | hypothetical protein SORBIDRAFT_06g032380 [Sorghum bicolor] |
RefSeq | XP_002533317.1 | 0 | 43 | 456 | 55 | 478 | catalytic, putative [Ricinus communis] |