| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb07g020270.1 |
| Family | GT20 |
| Protein Properties | Length: 866 Molecular Weight: 97985.6 Isoelectric Point: 6.6327 |
| Chromosome | Chromosome/Scaffold: 7 Start: 52610480 End: 52616205 |
| Description | trehalose phosphate synthase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 54 | 544 | 0 |
| ASSTERKIIVANFLPLNCTRDDTGKLSFSLDHDALLMQLKDGFSNETDAVYVGSLKVQVDPSEQDQVAQKLLREYRCIPTFLPSDLQQQFYHGFCKQQLW PLFHYMLPICLDKGELFDRNLFQAYVRANKLFADKVMEAINTDDDCVWVHDYHLMLLPTFLRKRLHRIKIGFFLHSPFPSSEIYRTLPVRDEILKSLLNA DLIGFQTFDYARHFLSCCSRLLGLHYESKRGYIGIEYFGRTVSLKILSVGVHVGRLESVLKLPATISKVQEIEQRYKGKILMLGVDDMDIFKGISLKLLG LELLLDRNPKLREKVVLVQIINPARSTGKDVQEAITEAVSVAKRINTKYGSSSYKPVVLIDHRIPFYEKIAFYAASDCCIVNAVRDGMNLVPYEYTVCRQ GNEEIDKLRGLDKDTHHTSTLIVSEFVGCSPSLSGAFRVNPWSVDDVADALCRATDLTESEKRLRHEKHYRYVSTHDVAYWARSFAQDLER | |||
| Full Sequence |
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| Protein Sequence Length: 866 Download |
| MVSKSYSNLL EMTSGDGFDF RQPFKSLPRV VTSPGIISDP DWDTISDGDS VGSASSTERK 60 IIVANFLPLN CTRDDTGKLS FSLDHDALLM QLKDGFSNET DAVYVGSLKV QVDPSEQDQV 120 AQKLLREYRC IPTFLPSDLQ QQFYHGFCKQ QLWPLFHYML PICLDKGELF DRNLFQAYVR 180 ANKLFADKVM EAINTDDDCV WVHDYHLMLL PTFLRKRLHR IKIGFFLHSP FPSSEIYRTL 240 PVRDEILKSL LNADLIGFQT FDYARHFLSC CSRLLGLHYE SKRGYIGIEY FGRTVSLKIL 300 SVGVHVGRLE SVLKLPATIS KVQEIEQRYK GKILMLGVDD MDIFKGISLK LLGLELLLDR 360 NPKLREKVVL VQIINPARST GKDVQEAITE AVSVAKRINT KYGSSSYKPV VLIDHRIPFY 420 EKIAFYAASD CCIVNAVRDG MNLVPYEYTV CRQGNEEIDK LRGLDKDTHH TSTLIVSEFV 480 GCSPSLSGAF RVNPWSVDDV ADALCRATDL TESEKRLRHE KHYRYVSTHD VAYWARSFAQ 540 DLERACKDHY SRRCWAIGFG LNFRVIALSP GFRKLSLEHF VSSYNKASRR AIFLDYDGTL 600 VAQSSINKAP SEEVISILNT LCNDPKNVVF IVSGRGRDSL DEWFSPCEKL GVAAEHGYFI 660 RWSKEAAWES SYSSPQQEWK HIAEPIMQVY TETTDGSSIE SKESALVWHY LDADHDFGSF 720 QAKELQDHLE RVLSNEPVVV KCGHYIVEVK PQGVSKGLAV NKLIHTLVKN GKAPDFLMCV 780 GNDRSDEDMF ECINGMTSND AISPTAPEVF ACSVGQKPSK AKYYVDDTSE VIRLLKNVTR 840 VSSQREDVNA SHGRVTFRDV LDYVD* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 1.0e-160 | 59 | 847 | 822 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 844 | 851 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 58 | 544 | 491 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 59 | 841 | 790 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 61 | 543 | 483 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EEC83577.1 | 0 | 1 | 865 | 1 | 862 | hypothetical protein OsI_29236 [Oryza sativa Indica Group] |
| GenBank | EEE68684.1 | 0 | 1 | 844 | 1 | 843 | hypothetical protein OsJ_27312 [Oryza sativa Japonica Group] |
| RefSeq | NP_001061805.1 | 0 | 1 | 865 | 1 | 862 | Os08g0414700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002445486.1 | 0 | 1 | 865 | 1 | 865 | hypothetical protein SORBIDRAFT_07g020270 [Sorghum bicolor] |
| RefSeq | XP_002462305.1 | 0 | 1 | 864 | 1 | 860 | hypothetical protein SORBIDRAFT_02g023610 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 142 | 544 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 769 | 80 | 844 | 0 |
| HO779327 | 515 | 97 | 611 | 0 |
| HO779327 | 239 | 607 | 845 | 0 |
| HO797286 | 481 | 375 | 852 | 0 |
| HO777775 | 75 | 1 | 73 | 0.09 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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