| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb07g021300.1 |
| Family | GT2 |
| Protein Properties | Length: 523 Molecular Weight: 58184.6 Isoelectric Point: 7.0518 |
| Chromosome | Chromosome/Scaffold: 7 Start: 55267891 End: 55278026 |
| Description | Nucleotide-diphospho-sugar transferases superfamily protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT2 | 127 | 303 | 2.2e-31 |
| VQIPMYNEREVYKLSIGAACALEWPTERFVIQVLDDSTDPVVKDLVEMECQRWKSKGVNIKYEVRGNRKGYKAGALKEGLKHDYVKDCEYIAMFDADFQP ESDFLLRTIPFLVHNPEIALVQTRWKFVNSDECLLTRFQEMSLDYHFKYEQEAGSSVYSFFGFNGTAGVWRISAIDD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 523 Download |
| MDPAARGGGH SIAEEAARLW ADFPVRVDWA AVAAQCASLW AHARALVLVP AVRLLVFLSL 60 AMTVMILLEK LFVCAVCLAV RAFRLGPHRR YRWEPITAAG SNGAAAGDDE ESGGGGHGEA 120 KYPMVLVQIP MYNEREVYKL SIGAACALEW PTERFVIQVL DDSTDPVVKD LVEMECQRWK 180 SKGVNIKYEV RGNRKGYKAG ALKEGLKHDY VKDCEYIAMF DADFQPESDF LLRTIPFLVH 240 NPEIALVQTR WKFVNSDECL LTRFQEMSLD YHFKYEQEAG SSVYSFFGFN GTAGVWRISA 300 IDDAGGWKDR TTVEDMDLAV RAMLQGWKFV YVGDIKVAAH TVTFIYYCFA IPVSVLLPEI 360 QIPLWGVVYV PTAITLLKAL GTPSSFHLVI LWVLFENVMS LHRIKAAISG LLDAGGRVNE 420 WVVTEKLGDT NKAKPGTNGS DAVKVIDVKL TEPLIPKLVK RRARFWERYH CSELFVGTCI 480 LMCGFYDLLL AKKGYYIFLF LQGTAFLVAG FGYVGTLPPC TA* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03030 | CelA | 3.0e-25 | 123 | 339 | 233 | + cellulose synthase catalytic subunit (UDP-forming). Cellulose synthase catalyzes the beta-1,4 polymerization of glucose residues in the formation of cellulose. In bacteria, the substrate is UDP-glucose. The synthase consists of two subunits (or domains in the frequent cases where it is encoded as a single polypeptide), the catalytic domain modelled here and the regulatory domain (pfam03170). The regulatory domain binds the allosteric activator cyclic di-GMP. The protein is membrane-associated and probably assembles into multimers such that the individual cellulose strands can self-assemble into multi-strand fibrils. | ||
| COG1215 | COG1215 | 2.0e-26 | 121 | 332 | 214 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
| cd06423 | CESA_like | 7.0e-30 | 127 | 315 | 191 | + CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan. | ||
| cd06421 | CESA_CelA_like | 2.0e-37 | 123 | 332 | 215 | + CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end. | ||
| cd06437 | CESA_CaSu_A2 | 9.0e-122 | 123 | 339 | 217 | + Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABF94194.1 | 0 | 50 | 521 | 37 | 511 | glycosyl transferase family 2 protein, putative, expressed [Oryza sativa (japonica cultivar-group)] |
| GenBank | EEE68748.1 | 0 | 75 | 519 | 22 | 520 | hypothetical protein OsJ_27439 [Oryza sativa Japonica Group] |
| RefSeq | NP_001061879.1 | 0 | 5 | 519 | 2 | 594 | Os08g0434500 [Oryza sativa (japonica cultivar-group)] |
| Swiss-Prot | Q6YWK8 | 0 | 5 | 519 | 2 | 570 | CSLAB_ORYSJ RecName: Full=Probable mannan synthase 11; AltName: Full=Cellulose synthase-like protein A11; AltName: Full=OsCslA11 |
| RefSeq | XP_002445548.1 | 0 | 1 | 522 | 1 | 522 | hypothetical protein SORBIDRAFT_07g021300 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4hg6_A | 4e-16 | 121 | 338 | 138 | 366 | B Chain B, Structure Of A Cellulose Synthase - Cellulose Translocation Intermediate |
