| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb07g021920.1 |
| Family | GT20 |
| Protein Properties | Length: 827 Molecular Weight: 91496.2 Isoelectric Point: 6.2993 |
| Chromosome | Chromosome/Scaffold: 7 Start: 56197166 End: 56200721 |
| Description | trehalose phosphatase/synthase 5 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 16 | 504 | 0 |
| VEARRIVVTHRLPLRAEPNPDAPHGFDFSLDADALPHQFARGLPRPVVFVGALPSAAASIPASDELAADLLARFACSPVFMEPSLHTDFYDRFCKHYLWP MLHYLLPFTPSGGGGGLSFKADLYRAYLTANTQYADRVFEHLNPDEDLVFIHDYHLFALPTILRHKSPRARIAFFLHSPFPTSEIFRAIPVREELLRALL NADLVGFHNYDYARHFLSACARLLGVSSHTHRGYIGIDYFGRAVVVKILSVGVDMGQLREVLSSPETAAKAKEVATRFAGRRVLLGVDDVDLFKGIDLKL LAMERLLVLRPELCGRVVLVQINNPARSPGRDTDTVRAEVQATRDRINARFASPGYEPIVMIDEPLTMHEKLAFYTSADICVVTAVRDGLNRIPYIYTVC RQEGPISGGVAGAPRESAIVLSEFVGCSTSLGGAVHVNPWNVDDVAEGMSSALRLDGRDKQMRQEKHYRYVVTHDIAYWGRSLDQDLQR | |||
| Full Sequence |
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| Protein Sequence Length: 827 Download |
| MASPSASDGE LSPFPVEARR IVVTHRLPLR AEPNPDAPHG FDFSLDADAL PHQFARGLPR 60 PVVFVGALPS AAASIPASDE LAADLLARFA CSPVFMEPSL HTDFYDRFCK HYLWPMLHYL 120 LPFTPSGGGG GLSFKADLYR AYLTANTQYA DRVFEHLNPD EDLVFIHDYH LFALPTILRH 180 KSPRARIAFF LHSPFPTSEI FRAIPVREEL LRALLNADLV GFHNYDYARH FLSACARLLG 240 VSSHTHRGYI GIDYFGRAVV VKILSVGVDM GQLREVLSSP ETAAKAKEVA TRFAGRRVLL 300 GVDDVDLFKG IDLKLLAMER LLVLRPELCG RVVLVQINNP ARSPGRDTDT VRAEVQATRD 360 RINARFASPG YEPIVMIDEP LTMHEKLAFY TSADICVVTA VRDGLNRIPY IYTVCRQEGP 420 ISGGVAGAPR ESAIVLSEFV GCSTSLGGAV HVNPWNVDDV AEGMSSALRL DGRDKQMRQE 480 KHYRYVVTHD IAYWGRSLDQ DLQRAGKDHA SMNFLSVGLA MNFRIVVLGP NFQKLSPEHI 540 NPSYHRTGNR LILLDYDGTV MIPQGLITRD PSQELISVLN ELCSDPKNTV FVVSGRRKDE 600 LARWLAPCER LGISAEHGYF TRWSRDSPWE SPNMLVDYDW KNIVEPVMKH YCDVTDGSYI 660 EAKETALVWH YEEADPVFGS SQAKELQDHL RDVLAKEPVS VKSGHQIVEV NPQEVGKGTA 720 VQRLIAALGA RGTMPDFILC VGDDGSDEDM FKAISAPPSS KSAFPEAAET FACTVGNKPS 780 LAKYYLEDPD EVLKMLKGLI DSSAAQQRPM AGGGRPQVSF EDPGSR* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 9.0e-144 | 19 | 799 | 823 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| cd03788 | GT1_TPS | 3.0e-156 | 19 | 503 | 488 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| pfam00982 | Glyco_transf_20 | 6.0e-166 | 19 | 504 | 490 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 5.0e-171 | 79 | 802 | 731 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| PLN02205 | PLN02205 | 0 | 19 | 807 | 798 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAY87814.1 | 0 | 2 | 821 | 35 | 844 | hypothetical protein OsI_09233 [Oryza sativa Indica Group] |
| GenBank | EAZ07161.1 | 0 | 18 | 822 | 23 | 820 | hypothetical protein OsI_29408 [Oryza sativa Indica Group] |
| RefSeq | NP_001061925.1 | 0 | 18 | 822 | 23 | 820 | Os08g0445700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002444439.1 | 0 | 1 | 826 | 1 | 826 | hypothetical protein SORBIDRAFT_07g021920 [Sorghum bicolor] |
| RefSeq | XP_002452959.1 | 0 | 19 | 821 | 50 | 846 | hypothetical protein SORBIDRAFT_04g035560 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 1.4013e-45 | 103 | 504 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 1.4013e-45 | 103 | 504 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 1.4013e-45 | 103 | 504 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 1.4013e-45 | 103 | 504 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1gz5_D | 1.4013e-45 | 103 | 504 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 748 | 79 | 814 | 0 |
| HO779327 | 497 | 81 | 572 | 0 |
| HO779327 | 254 | 568 | 821 | 0 |
| HO797286 | 469 | 339 | 803 | 0 |
| HO795511 | 470 | 336 | 803 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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