| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb07g023110.1 |
| Family | CE10 |
| Protein Properties | Length: 356 Molecular Weight: 37927.3 Isoelectric Point: 9.7875 |
| Chromosome | Chromosome/Scaffold: 7 Start: 57959533 End: 57960995 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 73 | 352 | 0 |
| VPASMDSRTGVASRDVVVDHGTGLAVRLYRPSRRAVAAGAGGGRRLPVLVYFHGGAFVVESAFDPVYHNYLNALTAKAGVIAVSVNYRLAPEHPLPAAYD DAWTALSWVLDNARRGGDPWLAKHGDASRLFLAGDSAGGNIAHNLAMRAGQQQGGAAARIKGVALLDPYFLGRYVSGGSQRSWDFICAGRYGMDHPYVDP MAALPAEVWRRLPSARVLMTVSDQDRLGPFQREYVDALRASGWRGQARLYVTPGEGHCYFLNNLASPKAAMHMATLAAFI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 356 Download |
| MAASPVLLVA AALCLCALLF GAGEAATKGG AAASSAFRSR ATDPNMEVKF DFSPFLIQYK 60 SGRVQRFMGT TFVPASMDSR TGVASRDVVV DHGTGLAVRL YRPSRRAVAA GAGGGRRLPV 120 LVYFHGGAFV VESAFDPVYH NYLNALTAKA GVIAVSVNYR LAPEHPLPAA YDDAWTALSW 180 VLDNARRGGD PWLAKHGDAS RLFLAGDSAG GNIAHNLAMR AGQQQGGAAA RIKGVALLDP 240 YFLGRYVSGG SQRSWDFICA GRYGMDHPYV DPMAALPAEV WRRLPSARVL MTVSDQDRLG 300 PFQREYVDAL RASGWRGQAR LYVTPGEGHC YFLNNLASPK AAMHMATLAA FINGS* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG2272 | PnbA | 1.0e-10 | 70 | 217 | 161 | + Carboxylesterase type B [Lipid metabolism] | ||
| cd00312 | Esterase_lipase | 2.0e-11 | 118 | 220 | 113 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| pfam00135 | COesterase | 4.0e-14 | 118 | 219 | 112 | + Carboxylesterase family. | ||
| COG0657 | Aes | 7.0e-29 | 45 | 353 | 327 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 4.0e-45 | 121 | 333 | 230 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAZ07335.1 | 0 | 6 | 353 | 9 | 330 | hypothetical protein OsI_29584 [Oryza sativa Indica Group] |
| GenBank | EAZ43068.1 | 0 | 6 | 353 | 9 | 330 | hypothetical protein OsJ_27658 [Oryza sativa Japonica Group] |
| RefSeq | NP_001062034.1 | 0 | 6 | 353 | 9 | 330 | Os08g0475100 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001063394.1 | 0 | 27 | 353 | 16 | 346 | Os09g0461500 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002444515.1 | 0 | 1 | 355 | 1 | 355 | hypothetical protein SORBIDRAFT_07g023110 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ed1_F | 7e-34 | 49 | 314 | 25 | 312 | A Chain A, Sugar Tongs Mutant S378p In Complex With Acarbose |
| PDB | 3ed1_E | 7e-34 | 49 | 314 | 25 | 312 | A Chain A, Sugar Tongs Mutant S378p In Complex With Acarbose |
| PDB | 3ed1_D | 7e-34 | 49 | 314 | 25 | 312 | A Chain A, Sugar Tongs Mutant S378p In Complex With Acarbose |
| PDB | 3ed1_C | 7e-34 | 49 | 314 | 25 | 312 | A Chain A, Sugar Tongs Mutant S378p In Complex With Acarbose |
| PDB | 3ed1_B | 7e-34 | 49 | 314 | 25 | 312 | A Chain A, Sugar Tongs Mutant S378p In Complex With Acarbose |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
