| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb07g023140.1 |
| Family | CE10 |
| Protein Properties | Length: 335 Molecular Weight: 35638.6 Isoelectric Point: 5.3881 |
| Chromosome | Chromosome/Scaffold: 7 Start: 57977647 End: 57978651 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 37 | 330 | 1.4013e-45 |
| DAATGVASKDVTLDPATGLWARLYLPVSARHPGGDSDRRRRRLPIVLYFHGGGLVVGSAADAPEHAFMNRLAARAGALAVSVEYRLAPEHPVPACYDDAW AALRLVVTPAPAADPWVRDHGDVARVFVLGFSAGANLAHNLTLRAGSEPDVLPRGARVLGMALLHPFFLSPPPPAAAAGDEVANYAWVRAKLAEMWEFAC GEGRTAAGPDDPRVNPLADGAPSLRRLGCGRVLVCLADDALVAEGKAYYEALLASGWDAADAELLDSAPADHEFHLREPDSDKAVLLMDRLVAR | |||
| Full Sequence |
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| Protein Sequence Length: 335 Download |
| MDPDFEVTFE FAPVIRQYKS GRVERLLPVN PVPPSVDAAT GVASKDVTLD PATGLWARLY 60 LPVSARHPGG DSDRRRRRLP IVLYFHGGGL VVGSAADAPE HAFMNRLAAR AGALAVSVEY 120 RLAPEHPVPA CYDDAWAALR LVVTPAPAAD PWVRDHGDVA RVFVLGFSAG ANLAHNLTLR 180 AGSEPDVLPR GARVLGMALL HPFFLSPPPP AAAAGDEVAN YAWVRAKLAE MWEFACGEGR 240 TAAGPDDPRV NPLADGAPSL RRLGCGRVLV CLADDALVAE GKAYYEALLA SGWDAADAEL 300 LDSAPADHEF HLREPDSDKA VLLMDRLVAR ITGS* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK10162 | PRK10162 | 2.0e-5 | 81 | 179 | 105 | + acetyl esterase; Provisional | ||
| pfam00135 | COesterase | 7.0e-8 | 59 | 185 | 141 | + Carboxylesterase family. | ||
| cd00312 | Esterase_lipase | 6.0e-8 | 76 | 185 | 124 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| COG0657 | Aes | 9.0e-24 | 4 | 332 | 330 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 2.0e-42 | 82 | 312 | 232 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACF86971.2 | 0 | 1 | 334 | 1 | 328 | unknown [Zea mays] |
| GenBank | EAZ07336.1 | 0 | 2 | 334 | 3 | 319 | hypothetical protein OsI_29585 [Oryza sativa Indica Group] |
| RefSeq | NP_001062035.1 | 0 | 2 | 334 | 3 | 319 | Os08g0475300 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001147183.1 | 0 | 1 | 334 | 1 | 328 | gibberellin receptor GID1L2 [Zea mays] |
| RefSeq | XP_002444519.1 | 0 | 1 | 334 | 1 | 334 | hypothetical protein SORBIDRAFT_07g023140 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2o7v_A | 2e-28 | 27 | 294 | 38 | 295 | A Chain A, Sugar Tongs Mutant S378p In Complex With Acarbose |
| PDB | 2o7r_A | 2e-28 | 27 | 294 | 38 | 295 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 2zsi_A | 7e-24 | 32 | 332 | 60 | 349 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 2zsh_A | 7e-24 | 32 | 332 | 60 | 349 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 3ed1_F | 2e-20 | 8 | 204 | 25 | 227 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DR969195 | 209 | 1 | 206 | 0 |
| DR735440 | 332 | 1 | 329 | 0 |
| EL690500 | 288 | 4 | 287 | 0 |
| DV513282 | 318 | 6 | 322 | 0 |
| DY822650 | 327 | 6 | 331 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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