| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb07g027310.1 |
| Family | GH19 |
| Protein Properties | Length: 303 Molecular Weight: 33302.6 Isoelectric Point: 5.1859 |
| Chromosome | Chromosome/Scaffold: 7 Start: 62401576 End: 62403516 |
| Description | Chitinase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 48 | 287 | 0 |
| DFFKAYQFEELFPKRNSDLAHAAGFWDYKAFITAAALFEPRGFGTTGGKEMGMMEVAAFLGHVGAKTSCGYNEAPDGETAWGLCYNHELSPSQSYCDDSN ELYPCVEGVEYYGRGALPVYWNYNYGIVGKGIKQDLLNHPELLEQNATLAFEAAIWRWMTPMKRKQPSAHDVFVGNWKPTKKDTLSKRYPGFGATMNILY GDAICGKGSTDKMNFIISHYQHYLGLMGVGRERSEDNLDC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 303 Download |
| MSGTRGAALL LLLLATLAAA VMAGGEKVCD KGWECSGSRF CCNETIGDFF KAYQFEELFP 60 KRNSDLAHAA GFWDYKAFIT AAALFEPRGF GTTGGKEMGM MEVAAFLGHV GAKTSCGYNE 120 APDGETAWGL CYNHELSPSQ SYCDDSNELY PCVEGVEYYG RGALPVYWNY NYGIVGKGIK 180 QDLLNHPELL EQNATLAFEA AIWRWMTPMK RKQPSAHDVF VGNWKPTKKD TLSKRYPGFG 240 ATMNILYGDA ICGKGSTDKM NFIISHYQHY LGLMGVGRER SEDNLDCSDQ VAFNPSSESS 300 DF* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00442 | lysozyme_like | 0.0002 | 151 | 213 | 63 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00182 | Glyco_hydro_19 | 1.0e-60 | 54 | 287 | 234 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 1.0e-91 | 50 | 287 | 238 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAZ07679.1 | 0 | 27 | 301 | 40 | 315 | hypothetical protein OsI_29936 [Oryza sativa Indica Group] |
| RefSeq | NP_001062281.1 | 0 | 27 | 301 | 40 | 315 | Os08g0522500 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001063549.1 | 0 | 26 | 301 | 45 | 320 | Os09g0494200 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001142334.1 | 0 | 19 | 301 | 38 | 320 | hypothetical protein LOC100274504 [Zea mays] |
| RefSeq | XP_002445877.1 | 0 | 1 | 302 | 1 | 302 | hypothetical protein SORBIDRAFT_07g027310 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3cql_B | 0 | 55 | 293 | 11 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3cql_A | 0 | 55 | 293 | 11 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 2z37_D | 0 | 54 | 294 | 10 | 244 | A Chain A, Crystal Structure Of Brassica Juncea Chitinase Catalytic Module (Bjchi3) |
| PDB | 2z37_C | 0 | 54 | 294 | 10 | 244 | A Chain A, Crystal Structure Of Brassica Juncea Chitinase Catalytic Module (Bjchi3) |
| PDB | 2z37_B | 0 | 54 | 294 | 10 | 244 | A Chain A, Crystal Structure Of Brassica Juncea Chitinase Catalytic Module (Bjchi3) |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
