| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb08g007160.1 |
| Family | GT47 |
| Protein Properties | Length: 524 Molecular Weight: 58624.4 Isoelectric Point: 6.0357 |
| Chromosome | Chromosome/Scaffold: 8 Start: 12100973 End: 12102642 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 85 | 442 | 0 |
| SCEGRYVYMLDVPSRFDILRDCVPGSPLFDDMWSWCAITVNAGLGPEIGPVAGNGSSDGDTDIIPSTGWYSTDQYSLEVIFHNWMRRYECLTDDPAAATA VYVPYYPALELHQHLCGFNTTVRDGPSEAFLRWLSSQPTWAALGGRDHFMVAAKTTWMFRREPGAGGGDEGCGNNFLGQPESRNMTVLTYESNIWAPRDI AVPYPSYFHPSSAGEVAAWQARARGAPRPFLFAFAGARRMKGQLAIRDRVFDVCDAAARRGRCGMLDCSHGLEGSITCRSPRKLVSLFTSARFCLQPRGD SFARRSSIDSVMAGCIPVFFHRPSTLKAQYRWHEPEPGRSDGDGRRYYVLINSKDVLE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 524 Download |
| MEAKYLVYYL LILGSWLLSC LLHFQYFHLS LSSFAAPRPA ALVVLPIALD ASFLASPTVE 60 ADNRRRSAAS SVVASPSPSP SSSPSCEGRY VYMLDVPSRF DILRDCVPGS PLFDDMWSWC 120 AITVNAGLGP EIGPVAGNGS SDGDTDIIPS TGWYSTDQYS LEVIFHNWMR RYECLTDDPA 180 AATAVYVPYY PALELHQHLC GFNTTVRDGP SEAFLRWLSS QPTWAALGGR DHFMVAAKTT 240 WMFRREPGAG GGDEGCGNNF LGQPESRNMT VLTYESNIWA PRDIAVPYPS YFHPSSAGEV 300 AAWQARARGA PRPFLFAFAG ARRMKGQLAI RDRVFDVCDA AARRGRCGML DCSHGLEGSI 360 TCRSPRKLVS LFTSARFCLQ PRGDSFARRS SIDSVMAGCI PVFFHRPSTL KAQYRWHEPE 420 PGRSDGDGRR YYVLINSKDV LEGRVDIEEE LSRYTDEEVA AMREEVIKMM PRFLYKDPRV 480 RFEGEMRDAF DITIDEMIAR MRRIKNGENL IWKGDDRDED FDS* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 6.0e-38 | 86 | 404 | 333 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABA96790.1 | 0 | 1 | 519 | 1 | 521 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
| DDBJ | BAH95576.1 | 0 | 154 | 519 | 94 | 460 | Os12g0224400 [Oryza sativa Japonica Group] |
| GenBank | EEC69035.1 | 0 | 102 | 519 | 1 | 385 | hypothetical protein OsI_37846 [Oryza sativa Indica Group] |
| GenBank | EEE52961.1 | 0 | 102 | 519 | 1 | 418 | hypothetical protein OsJ_35605 [Oryza sativa Japonica Group] |
| RefSeq | XP_002443053.1 | 0 | 1 | 523 | 1 | 523 | hypothetical protein SORBIDRAFT_08g007160 [Sorghum bicolor] |
