| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb08g017820.1 |
| Family | CE10 |
| Protein Properties | Length: 336 Molecular Weight: 36078.6 Isoelectric Point: 5.3268 |
| Chromosome | Chromosome/Scaffold: 8 Start: 47829763 End: 47830809 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 50 | 334 | 0 |
| GVTSRDVVISPNVSARLYLPRLGDGNGDAKLPILVYYHGGGFCIGSAFNPIFHAYFNAFTSLATALVVSVEYRLAPEHPVPAAYADSWDALAWVVSHSHL ASSSAARDPWIAGHADFSRLYLGGESAGANIAHHMAMRAAAAAEGELAHGRARIRGLVMVHPYFLGTDRVPSDDLSAETRESLASLWRVMCPSSTAGDDD PLINPLVDGAPALASLACARVLVCVAEGDVLRDRGRAYYDRLRASGWPGEAEFWQAPDRGHTFHFMDPCCDEAVAQDKVISDFLN | |||
| Full Sequence |
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| Protein Sequence Length: 336 Download |
| MAAAPVTPPP ASADDELVYE SLPCIRVYKN RVERYFGSEF VPASTDAATG VTSRDVVISP 60 NVSARLYLPR LGDGNGDAKL PILVYYHGGG FCIGSAFNPI FHAYFNAFTS LATALVVSVE 120 YRLAPEHPVP AAYADSWDAL AWVVSHSHLA SSSAARDPWI AGHADFSRLY LGGESAGANI 180 AHHMAMRAAA AAEGELAHGR ARIRGLVMVH PYFLGTDRVP SDDLSAETRE SLASLWRVMC 240 PSSTAGDDDP LINPLVDGAP ALASLACARV LVCVAEGDVL RDRGRAYYDR LRASGWPGEA 300 EFWQAPDRGH TFHFMDPCCD EAVAQDKVIS DFLNR* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00312 | Esterase_lipase | 0.002 | 78 | 178 | 110 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| COG2272 | PnbA | 0.001 | 79 | 178 | 116 | + Carboxylesterase type B [Lipid metabolism] | ||
| pfam00135 | COesterase | 3.0e-5 | 66 | 178 | 129 | + Carboxylesterase family. | ||
| COG0657 | Aes | 5.0e-26 | 59 | 317 | 262 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 1.0e-44 | 83 | 314 | 239 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EEC83733.1 | 0 | 14 | 335 | 14 | 327 | hypothetical protein OsI_29586 [Oryza sativa Indica Group] |
| RefSeq | NP_001062036.1 | 0 | 14 | 335 | 14 | 327 | Os08g0475400 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001149234.1 | 0 | 14 | 334 | 14 | 326 | gibberellin receptor GID1L2 [Zea mays] |
| RefSeq | NP_001150584.1 | 0 | 12 | 335 | 12 | 327 | gibberellin receptor GID1L2 [Zea mays] |
| RefSeq | XP_002442315.1 | 0 | 1 | 335 | 1 | 335 | hypothetical protein SORBIDRAFT_08g017820 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2o7v_A | 1e-38 | 47 | 302 | 49 | 300 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 2o7r_A | 1e-38 | 47 | 302 | 49 | 300 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_F | 2e-30 | 41 | 334 | 52 | 348 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_E | 2e-30 | 41 | 334 | 52 | 348 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_D | 2e-30 | 41 | 334 | 52 | 348 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX611572 | 250 | 14 | 262 | 0 |
| EE048049 | 247 | 14 | 260 | 0 |
| FL829875 | 253 | 14 | 266 | 0 |
| FL930662 | 253 | 14 | 266 | 0 |
| FL951782 | 253 | 14 | 266 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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