| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb08g018880.1 |
| Family | GT47 |
| Protein Properties | Length: 587 Molecular Weight: 65423.2 Isoelectric Point: 9.3525 |
| Chromosome | Chromosome/Scaffold: 8 Start: 49357706 End: 49359466 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 174 | 511 | 0 |
| CAGRYIYVQDLPSRFNADLLRDCRSLSEWTDMCRHVANAGMGPRLTRTGGVLPPTGWYDTNQFTLEVIFHNRMRQYGCLTADASRASAVYVPYYAGLDVG RHLWGFSNDVRDALAEDLVGWLRSSPAWAAHGGRDHFLVGGRIAWDLRREDGGEWGSRLLFLPEARNMTALVLESGPWHVGDVGVPYPTYFHPSRAAEVA SWQRTLRRARRPWLFAFVGARRPGDTLRDSVMDQCARSRRCGLLQCGRGRRRDCYAPGNVMRHLKSAAFCLQPPGDSYTRRSAFDAMLAGCVPVFFHPGS AYTQYRWHLPADHTRYSVFVPGDSVRNGTVRVVDVLRR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 587 Download |
| MAGVQASAVL RAGRWLLPLT IPACCVVWML LVFSPPTPEL DAGHRQSFHV IVGETVAAIE 60 RRGTPPVLER VQESPPPAEL LARTKTPSSS PPPSPESEET IDTSPPSPER RPRAQPKQPL 120 PPERERILDA SSQPELAPVR QSRTGIPASP PPPQPSHQHL SRAQTKPAAV SDRCAGRYIY 180 VQDLPSRFNA DLLRDCRSLS EWTDMCRHVA NAGMGPRLTR TGGVLPPTGW YDTNQFTLEV 240 IFHNRMRQYG CLTADASRAS AVYVPYYAGL DVGRHLWGFS NDVRDALAED LVGWLRSSPA 300 WAAHGGRDHF LVGGRIAWDL RREDGGEWGS RLLFLPEARN MTALVLESGP WHVGDVGVPY 360 PTYFHPSRAA EVASWQRTLR RARRPWLFAF VGARRPGDTL RDSVMDQCAR SRRCGLLQCG 420 RGRRRDCYAP GNVMRHLKSA AFCLQPPGDS YTRRSAFDAM LAGCVPVFFH PGSAYTQYRW 480 HLPADHTRYS VFVPGDSVRN GTVRVVDVLR RFGRSQVAAM REQVIRMIPG IVYRDPRAPS 540 GEFRDAFDVA VDGLIRRVSR IKQGLPPGEE EDDDGSRHWD GYFDTR* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-59 | 173 | 512 | 358 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABA99677.1 | 0 | 174 | 586 | 97 | 526 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
| GenBank | EAY83600.1 | 0 | 174 | 586 | 97 | 526 | hypothetical protein OsI_38822 [Oryza sativa Indica Group] |
| RefSeq | XP_002442366.1 | 0 | 1 | 586 | 1 | 586 | hypothetical protein SORBIDRAFT_08g018880 [Sorghum bicolor] |
