| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb09g020930.1 |
| Family | GT8 |
| Protein Properties | Length: 632 Molecular Weight: 72920.4 Isoelectric Point: 8.8782 |
| Chromosome | Chromosome/Scaffold: 9 Start: 50350623 End: 50356022 |
| Description | plant glycogenin-like starch initiation protein 2 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT8 | 292 | 515 | 6.09565e-43 |
| KSRLFSVDRRREAYATILHSASEYVCGAITAAQSIRQAGSTRDLVILVDETISDHHRRGLEAAGWKVRIIQRIRNPKAERDAYNEWNYSKFRLWQLTDYD KIIFIDADLLILRNVDFLFAMPEITATGNNATLFNSGVMVIEPSNCTFQLLMDHINEITSYNGGDQGYLNEIFTWWHRIPKHMNFLKHFWEGDSQAMKAK KTQLFGADPPILYVLHYLGLKPWL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 632 Download |
| MGPLEPRYRP AGAPEDTTKR RASKSKSFKD VENFEVIVLE KSCGCKFKSL RILLIAIISA 60 TVLTLVTPTL YEHQLQSASR YVDVGWMWDK TSSDPRYVSS VDVRWEDVYK ALGNLRSGNQ 120 NLKVGLLNFN STEYGSWTQL LSDSHVSIIR LEHAKDSITW QTLYPEWIDE EEETEIPSCP 180 SLPEPDVRRD VRFDVIAVKL PCTHVAGWSR DVARLHLQLS AAKLAVTSSK RNHKVHVLFV 240 TECFPIPNLF PCKNLVRHEG NAWLYSPDSK ALREKLRLPV GSCELAVPLK AKSRLFSVDR 300 RREAYATILH SASEYVCGAI TAAQSIRQAG STRDLVILVD ETISDHHRRG LEAAGWKVRI 360 IQRIRNPKAE RDAYNEWNYS KFRLWQLTDY DKIIFIDADL LILRNVDFLF AMPEITATGN 420 NATLFNSGVM VIEPSNCTFQ LLMDHINEIT SYNGGDQGYL NEIFTWWHRI PKHMNFLKHF 480 WEGDSQAMKA KKTQLFGADP PILYVLHYLG LKPWLCFKDY DCNWNNAGMR EFASDVAHAR 540 WWKVHDKMPR KLQSYCLLRS RQKASLEWDR RQAEKANSED GHWRRNITDT RLKTCFEKFC 600 FWESMLWHWG ENNNRTKSIP MAVKTASLAR S* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00505 | Glyco_transf_8 | 7.0e-11 | 308 | 514 | 245 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
| PLN00176 | PLN00176 | 5.0e-18 | 284 | 464 | 220 | + galactinol synthase | ||
| cd06914 | GT8_GNT1 | 8.0e-20 | 305 | 465 | 171 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. | ||
| pfam01501 | Glyco_transf_8 | 3.0e-40 | 306 | 516 | 253 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
| cd02537 | GT8_Glycogenin | 1.0e-73 | 303 | 548 | 256 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAS90653.1 | 0 | 1 | 626 | 1 | 671 | putative glycogenin [Oryza sativa Japonica Group] |
| GenBank | ACR35990.1 | 0 | 1 | 626 | 1 | 630 | unknown [Zea mays] |
| GenBank | EEC79261.1 | 0 | 1 | 626 | 1 | 671 | hypothetical protein OsI_20036 [Oryza sativa Indica Group] |
| RefSeq | NP_001152387.1 | 0 | 1 | 626 | 1 | 631 | LOC100286027 [Zea mays] |
| RefSeq | XP_002441128.1 | 0 | 1 | 631 | 1 | 631 | hypothetical protein SORBIDRAFT_09g020930 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3u2x_B | 3e-23 | 303 | 514 | 5 | 221 | A Chain A, Human Beta-Hexosaminidase B |
| PDB | 3u2x_A | 3e-23 | 303 | 514 | 5 | 221 | A Chain A, Human Beta-Hexosaminidase B |
| PDB | 3u2v_B | 3e-23 | 303 | 514 | 5 | 221 | A Chain A, Human Beta-Hexosaminidase B |
| PDB | 3u2v_A | 3e-23 | 303 | 514 | 5 | 221 | A Chain A, Human Beta-Hexosaminidase B |
| PDB | 3u2u_B | 3e-23 | 303 | 514 | 5 | 221 | A Chain A, Human Beta-Hexosaminidase B |
