| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb10g005120.1 |
| Family | GT47 |
| Protein Properties | Length: 413 Molecular Weight: 47077.4 Isoelectric Point: 7.5141 |
| Chromosome | Chromosome/Scaffold: 10 Start: 4595096 End: 4596427 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 58 | 363 | 0 |
| ERRFKVYVYEEGEPPILHAGPCKDIYTIEGRFIEQLELMAPPPPAGGGGGARTSDPARAHAFFLPFSVSKMVQFAYRPDTYDKTPLRAIVADYVRVVASR HPYWNRSAGADHFMLSCHDWGPEASRGHPELHANGIRALCNANTSEGFRPGQDVSVPEINLYTGDMPRQLLAPPAPPLASRPFLAFFAGGRHGHVRDLLL RRWKGHDPDVFPVYEHEHEHSHGRRQQDGAPLDYYWYMRRARFCLCPSGYEVASPRVVEAIHAECVPVILSDGYALPFADVLRWEAFSVAVPVADIPRLR EVLERI | |||
| Full Sequence |
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| Protein Sequence Length: 413 Download |
| MLSWPASTAT RPRSTGEYSI DDGDPNPTER NTNDSHLIFH EYVRYGDCEA SRSYREMERR 60 FKVYVYEEGE PPILHAGPCK DIYTIEGRFI EQLELMAPPP PAGGGGGART SDPARAHAFF 120 LPFSVSKMVQ FAYRPDTYDK TPLRAIVADY VRVVASRHPY WNRSAGADHF MLSCHDWGPE 180 ASRGHPELHA NGIRALCNAN TSEGFRPGQD VSVPEINLYT GDMPRQLLAP PAPPLASRPF 240 LAFFAGGRHG HVRDLLLRRW KGHDPDVFPV YEHEHEHSHG RRQQDGAPLD YYWYMRRARF 300 CLCPSGYEVA SPRVVEAIHA ECVPVILSDG YALPFADVLR WEAFSVAVPV ADIPRLREVL 360 ERIPAPEVER LQRGVRLVKR HFMLHQPPER LDMFNMILHS VWLRRLNLRL NR* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-56 | 57 | 363 | 321 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD44815.1 | 0 | 52 | 411 | 129 | 512 | putative pectin-glucuronyltransferase [Oryza sativa Japonica Group] |
| EMBL | CAH67778.1 | 0 | 52 | 412 | 95 | 441 | H0201G08.5 [Oryza sativa (indica cultivar-group)] |
| GenBank | EEC80122.1 | 0 | 52 | 411 | 129 | 543 | hypothetical protein OsI_21883 [Oryza sativa Indica Group] |
| RefSeq | NP_001052025.1 | 0 | 52 | 412 | 95 | 441 | Os04g0109900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002437936.1 | 0 | 1 | 402 | 1 | 402 | hypothetical protein SORBIDRAFT_10g005120 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EE679499 | 235 | 168 | 402 | 0 |
| GE475605 | 293 | 110 | 402 | 0 |
| FE523338 | 298 | 52 | 349 | 0 |
| GW864815 | 331 | 73 | 400 | 0 |
| DV974217 | 289 | 110 | 398 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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