| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb10g008950.1 |
| Family | CE10 |
| Protein Properties | Length: 318 Molecular Weight: 34452.7 Isoelectric Point: 4.6403 |
| Chromosome | Chromosome/Scaffold: 10 Start: 9469914 End: 9470901 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 19 | 313 | 0 |
| DRRIDRLMGTETVPAGFDPTTGVTSKDVVIDSDAGLYVRLYLPDMAATGTGSRRSPPNDDDDKKLPVLVYFHGGGFVTQSAASPVYQRFLNALAAKAGLL IVSVNYRLAPEHPLPAGYEDSFRAFTWTTSAGNGGDGDPWLSRHGDLRRVFLAGDSAGGNIDHNVAMMADDAAADRGEPVDGEAPASRARMEKLWGFVCP DATDGVDDPRVNPLVAAAAPSLRDLPCERVLVCAAELDSLLPRDRAYYEAIKATRGWRGRVEWFESQGQDHVFFLFKPVCGEAVALMDRLAAFFA | |||
| Full Sequence |
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| Protein Sequence Length: 318 Download |
| MDPSSDIILD TPYFRIYSDR RIDRLMGTET VPAGFDPTTG VTSKDVVIDS DAGLYVRLYL 60 PDMAATGTGS RRSPPNDDDD KKLPVLVYFH GGGFVTQSAA SPVYQRFLNA LAAKAGLLIV 120 SVNYRLAPEH PLPAGYEDSF RAFTWTTSAG NGGDGDPWLS RHGDLRRVFL AGDSAGGNID 180 HNVAMMADDA AADRGEPVDG EAPASRARME KLWGFVCPDA TDGVDDPRVN PLVAAAAPSL 240 RDLPCERVLV CAAELDSLLP RDRAYYEAIK ATRGWRGRVE WFESQGQDHV FFLFKPVCGE 300 AVALMDRLAA FFAGKTE* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00312 | Esterase_lipase | 8.0e-8 | 74 | 177 | 116 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| COG2272 | PnbA | 2.0e-9 | 32 | 177 | 156 | + Carboxylesterase type B [Lipid metabolism] | ||
| pfam00135 | COesterase | 1.0e-11 | 73 | 177 | 115 | + Carboxylesterase family. | ||
| COG0657 | Aes | 8.0e-28 | 19 | 313 | 312 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 3.0e-43 | 86 | 293 | 227 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG31893.1 | 0 | 3 | 315 | 4 | 315 | gibberellin receptor GID1L2 [Zea mays] |
| RefSeq | NP_001140223.1 | 0 | 3 | 315 | 4 | 315 | hypothetical protein LOC100272258 [Zea mays] |
| RefSeq | NP_001141390.1 | 0 | 1 | 315 | 1 | 324 | hypothetical protein LOC100273481 [Zea mays] |
| RefSeq | NP_001152234.1 | 0 | 1 | 315 | 1 | 324 | gibberellin receptor GID1L2 [Zea mays] |
| RefSeq | XP_002436796.1 | 0 | 1 | 317 | 1 | 317 | hypothetical protein SORBIDRAFT_10g008950 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2o7v_A | 9e-31 | 2 | 198 | 13 | 192 | B Chain B, Reassembly And Co-Crystallization Of A Family 9 Processive Endoglucanase From Separately Expressed Gh9 And Cbm3c Modules |
| PDB | 2o7r_A | 9e-31 | 2 | 198 | 13 | 192 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 2zsi_A | 2e-28 | 31 | 311 | 60 | 347 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 2zsh_A | 2e-28 | 31 | 311 | 60 | 347 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| PDB | 3ed1_F | 5e-27 | 17 | 270 | 47 | 309 | B Chain B, Structural Basis Of Gibberellin(Ga3)-Induced Della Recognition By The Gibberellin Receptor |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DV516369 | 300 | 3 | 287 | 0 |
| EE164195 | 282 | 5 | 272 | 0 |
| EE035112 | 275 | 3 | 263 | 0 |
| EB165963 | 268 | 3 | 256 | 0 |
| DV512881 | 270 | 3 | 258 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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