| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb10g030970.1 |
| Family | GT48 |
| Protein Properties | Length: 1966 Molecular Weight: 226621 Isoelectric Point: 9.3701 |
| Chromosome | Chromosome/Scaffold: 10 Start: 60615398 End: 60629715 |
| Description | glucan synthase-like 12 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT48 | 1070 | 1821 | 0 |
| VPTNLDARRRISFFANSLFMDMPNAPKVRNMLPFSILTPYYKEDVLFSLQNLEEPNEDGVSILFYLQKIYPDEWKNFLERVGCKNEEELREDEELEEKLR LWASYRGQTLTRTVRGMMYYRKALELQAFLDMAKDDDLMEGYRATEVMPEDSQLMTQCKAIADMKFTYVVSCQQYGIQKRSNEPCAHDILRLMTEYPSLR VAYIDEVEAPSQDRNKKIEKVYYSVLVKASVTKPNEPGQSLDQVIYKIKLPGNAILGEGKPENQNHAIIFTRGECLQTIDMNQEHYMEEALKMRNLLQEF QKKHDGVRYPSILGVREHIFTGSVSSLAWFMSNQETSFVTIGQRVLANPLRVRFHYGHPDVFDRLFHVTRGGVSKASKIINLSEDIFAGFNSTLREGNVT HHEYMQVGKGRDVGLNQISLFEAKIANGNGEQTLSRDIYRLGHRFDFFRMLSCYYTTIGFYFSTMITVWTVYVFLYGRLYLVLSGLDEALATGRRFVRNA PLQVALASESFVQLGFLMALPMMMEIGLERGFRTALSDFILMQLQLASVFFTFSLGTKTHYYGRTLLHGGAEYRATGRGFVVFHAKFADNYRLYSRSHFV KGIELMILLVVYEIFGQSYRGAITYIFITVSMWFMVGTWLFAPFLFNPSGFEWQKIVDDWTDWHKWISNRGGIGVAPEKSWESWWEKEQEPLRYSGKRGT IVEILLALRFFIYQYGLVYHLNITKKITKDNQSVLVYCFSWVVIFVILLVMK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1966 Download |
| MAAPGRRTAD VSSSSPAPSP SPAAPSSTGR RLLRTQTVGN LGESIFDSEV VPSSLVEIAP 60 ILRVANEVEA TNPRVAYLCR FYAFEKAHRL DPTSSGRGVR QFKTALLQRL ERENDPTLKG 120 RVHQSDAREM QRFYREYYKK YIQALQNAAD KADRALLTKA YQTAAVLFEV LRAVNVSQSV 180 EVDQAILDTH NKVEEKKKLF LPCNILPLDP ESTGQAIMLY PEIQAAVYAL RNTRGLPWPK 240 DQDKKPDEKN TGKDLLDWLQ AMFGFQKDNV SNQREHLILL LANVHIRKIP KADLQPKLDD 300 KALDDVMKKL FKNYKKWCKY LGRKSSLWLP TIQQEVQQRK LLYMGLYLLI WGEAANLRFM 360 PECICYIYHH MAFELYGMLA GNVSPMTGEN VKPAYGGDEE AFLMKVVTPI YKVIEKEAER 420 SKTMKSKHSH WRNYDDLNEY FWSVDCFRLG WPMRADADFF KTPKDAYPNL LNGENRSAGN 480 VHWMGKVNFV EIRSFWHIFR SFDRMWIFLI LSLQAMIIIA WNGGTPSDIF DAGVFKKVLS 540 IFITAAILKL GQAILDLVFG WKARRSMSFA VKLRYVLKLI SAAAWVVILP VTYAYTWENP 600 TGLARTIKSW LGDGQNQPSL YILAIVIYMA PNILASMLFL FPFMRRFLES SNVKVITIMM 660 WWSQPRLFVG RGMHEGAFSL FKYTMFWIIL LAMKLIVSFY IEIKPLVQPT KDIMREPIRT 720 FQWHEFFPHG TNNIGVVISL WAPIILVYFM DTQIWYALFS TLIGGIYGAY RRLGEIRTLG 780 MLRSRFESLP EAFNERLIPS DANKSKGLRA AFLSRPKVPG DEREREKRAA RFAQMWNVII 840 TSFREEDLID NREMDLLLVP YCKDRELDIF QWPPFLLASK IPIALDMAAD SGGKDRDLTK 900 RIKSDPYFSF AIRECYASFK NIINTLVFGQ REKDVLAKIF TVVDEHIEDG TLIKDLNMRN 960 LPALSKKFVE LLELLQKNKE EDLGQVVILF QDMLEVVTRD IMEEQDQLST LLDSIHGAHS 1020 RKHEGITPLD QQDQLFAKAI KFPVEESNAW TEKIKRLHLL LTVKESAMDV PTNLDARRRI 1080 SFFANSLFMD MPNAPKVRNM LPFSILTPYY KEDVLFSLQN LEEPNEDGVS ILFYLQKIYP 1140 DEWKNFLERV GCKNEEELRE DEELEEKLRL WASYRGQTLT RTVRGMMYYR KALELQAFLD 1200 MAKDDDLMEG YRATEVMPED SQLMTQCKAI ADMKFTYVVS CQQYGIQKRS NEPCAHDILR 1260 LMTEYPSLRV AYIDEVEAPS QDRNKKIEKV YYSVLVKASV TKPNEPGQSL DQVIYKIKLP 1320 GNAILGEGKP ENQNHAIIFT RGECLQTIDM NQEHYMEEAL KMRNLLQEFQ KKHDGVRYPS 1380 ILGVREHIFT GSVSSLAWFM SNQETSFVTI GQRVLANPLR VRFHYGHPDV FDRLFHVTRG 1440 GVSKASKIIN LSEDIFAGFN STLREGNVTH HEYMQVGKGR DVGLNQISLF EAKIANGNGE 1500 QTLSRDIYRL GHRFDFFRML SCYYTTIGFY FSTMITVWTV YVFLYGRLYL VLSGLDEALA 1560 TGRRFVRNAP LQVALASESF VQLGFLMALP MMMEIGLERG FRTALSDFIL MQLQLASVFF 1620 TFSLGTKTHY YGRTLLHGGA EYRATGRGFV VFHAKFADNY RLYSRSHFVK GIELMILLVV 1680 YEIFGQSYRG AITYIFITVS MWFMVGTWLF APFLFNPSGF EWQKIVDDWT DWHKWISNRG 1740 GIGVAPEKSW ESWWEKEQEP LRYSGKRGTI VEILLALRFF IYQYGLVYHL NITKKITKDN 1800 QSVLVYCFSW VVIFVILLVM KTVSVGRRRF SAEFQLVFRL IKGLIFITFT AIVVILIAIP 1860 GMTVLDIFVC ILAFMPTGWG LLLIAQAIRP VIQKIGLWGS IKALARGYEI LMGLLLFTPI 1920 AFLAWFPFVS EFQTRMLFNQ AFSRGLQISR ILGGHKKDRG TRNKE* 1980 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03772 | Competence | 0.005 | 494 | 592 | 100 | + Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane. These proteins contain a highly conserved motif in the amino terminal transmembrane region that has two histidines that may form a metal binding site. | ||
| pfam04652 | DUF605 | 1.0e-9 | 58 | 172 | 122 | + Vta1 like. Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. | ||
| pfam14288 | FKS1_dom1 | 1.0e-55 | 338 | 454 | 118 | + 1,3-beta-glucan synthase subunit FKS1, domain-1. The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364. | ||
| pfam02364 | Glucan_synthase | 0 | 1070 | 1817 | 819 | + 1,3-beta-glucan synthase component. This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000148 | 1,3-beta-D-glucan synthase complex |
| GO:0003843 | 1,3-beta-D-glucan synthase activity |
| GO:0006075 | (1->3)-beta-D-glucan biosynthetic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD23015.1 | 0 | 30 | 1965 | 35 | 1969 | putative callose synthase 1 catalytic subunit [Oryza sativa Japonica Group] |
| DDBJ | BAD62105.1 | 0 | 30 | 1965 | 28 | 1959 | putative callose synthase 1 catalytic subunit [Oryza sativa Japonica Group] |
| GenBank | EEE58116.1 | 0 | 30 | 1965 | 35 | 1918 | hypothetical protein OsJ_09005 [Oryza sativa Japonica Group] |
| RefSeq | XP_002439067.1 | 0 | 1 | 1965 | 1 | 1965 | hypothetical protein SORBIDRAFT_10g030970 [Sorghum bicolor] |
| RefSeq | XP_002453103.1 | 0 | 15 | 1965 | 14 | 1942 | hypothetical protein SORBIDRAFT_04g038510 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2lxm_A | 0.009 | 62 | 171 | 21 | 128 | B Chain B, Lip5-chmp5 |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| callose biosynthesis | 13-BETA-GLUCAN-SYNTHASE-RXN | EC-2.4.1.34 | 1,3-β-glucan synthase |
