| Basic Information | |
|---|---|
| Species | Sorghum bicolor |
| Cazyme ID | Sb3219s002010.1 |
| Family | GH19 |
| Protein Properties | Length: 310 Molecular Weight: 32030.6 Isoelectric Point: 5.678 |
| Chromosome | Chromosome/Scaffold: 3219 Start: 56 End: 983 |
| Description | basic chitinase |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 83 | 309 | 0 |
| VASIISESLFNQMLLHRNDAACPANGFYTYSAFIAAANAFPGFGTTGGADTQKRELAAFLAQTSHETTGGWATAPDGAYAWGYCFKEEQGAASGPDYCEP STQWPCAAGKKYYGRGPIQISYNYNYGAAGQAIGAGILANPDLVASDPTVSFETAVWFWMTPQSPKPSCHAVMTGQWTPSGADTAAGRLPGYGVVTNIIN GGLECGKGADSRVADRIGFYKRYCDLL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 310 Download |
| MMRALAVLAM VALFAASSAR AEQCGTQAGG ALCPNCLCCS KFGWCGSTSD YCGSGCQSQC 60 TGSCGSTPST PTPTPSSGGG GSVASIISES LFNQMLLHRN DAACPANGFY TYSAFIAAAN 120 AFPGFGTTGG ADTQKRELAA FLAQTSHETT GGWATAPDGA YAWGYCFKEE QGAASGPDYC 180 EPSTQWPCAA GKKYYGRGPI QISYNYNYGA AGQAIGAGIL ANPDLVASDP TVSFETAVWF 240 WMTPQSPKPS CHAVMTGQWT PSGADTAAGR LPGYGVVTNI INGGLECGKG ADSRVADRIG 300 FYKRYCDLLX 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00442 | lysozyme_like | 1.0e-13 | 139 | 281 | 143 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00187 | Chitin_bind_1 | 8.0e-14 | 23 | 59 | 37 | + Chitin recognition protein. | ||
| cd06921 | ChtBD1_GH19_hevein | 2.0e-15 | 22 | 59 | 38 | + Hevein or Type 1 chitin binding domain subfamily co-occuring with family 19 glycosyl hydrolases or with barwin domains. This subfamily includes Hevein, a major IgE-binding allergen in natural rubber latex. ChtBD1 is a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements. | ||
| cd00325 | chitinase_glyco_hydro_19 | 3.0e-127 | 87 | 309 | 223 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| pfam00182 | Glyco_hydro_19 | 2.0e-134 | 86 | 309 | 224 | + Chitinase class I. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAT40012.1 | 0 | 1 | 309 | 1 | 304 | chitinase [Zea mays subsp. parviglumis] |
| GenBank | AAT40015.1 | 0 | 1 | 309 | 1 | 303 | chitinase [Zea mays subsp. parviglumis] |
| GenBank | AAT40016.1 | 0 | 1 | 309 | 1 | 304 | chitinase [Zea mays subsp. parviglumis] |
| GenBank | AAT40017.1 | 0 | 1 | 309 | 1 | 303 | chitinase [Zea mays subsp. parviglumis] |
| RefSeq | XP_002488863.1 | 0 | 1 | 309 | 1 | 309 | hypothetical protein SORBIDRAFT_3219s002010 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3iwr_B | 0 | 22 | 306 | 2 | 279 | A Chain A, The Structure Of Soybean Peroxidase |
| PDB | 3iwr_A | 0 | 22 | 306 | 2 | 279 | A Chain A, The Structure Of Soybean Peroxidase |
| PDB | 2dkv_A | 0 | 22 | 306 | 2 | 279 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
| PDB | 4dyg_B | 0 | 82 | 309 | 2 | 227 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
| PDB | 4dyg_A | 0 | 82 | 309 | 2 | 227 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
