Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si001155m |
Family | GT47 |
Protein Properties | Length: 499 Molecular Weight: 55824.2 Isoelectric Point: 9.3411 |
Chromosome | Chromosome/Scaffold: 5 Start: 39628597 End: 39633354 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 112 | 422 | 0 |
LRVYVYEMPSKFTYDLLRLFRDSYRETDNLTSNGSPVHRLIEQHSIDYWLWADLIAPESRRLLKNVLRVQRQEEADIFYVPFFTTISYFLLEKQECKALY REALKWVTNQPAWQRSEGRDHVIPVHHPWSFKSVRSFVKKAIWLLPDMDSTGNWYKPGQVYLEKDVILPYVPNVDLCDSKCVSETQSKRSILLFFRGRLK RNAGGKIRSKLVEELKGAEGIVIEEGSAGAQGKTAAQDGMRKSLFCLSPAGDTPSSARLFDAIVSGCIPVIISDELELPFEGILDYREIALFVSSTDALQ PGWLMNYLRRI |
Full Sequence |
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Protein Sequence Length: 499 Download |
MAGKQFASLA HARPASASSR RLLAAAGVLI LLSAAYFLLL SPSSPRPTAA VLASPSSSTT 60 TSFLASLESF LAAPHPSDSA PAPGDLDAAI RAQEEARLYG DPAWPAPAAG PLRVYVYEMP 120 SKFTYDLLRL FRDSYRETDN LTSNGSPVHR LIEQHSIDYW LWADLIAPES RRLLKNVLRV 180 QRQEEADIFY VPFFTTISYF LLEKQECKAL YREALKWVTN QPAWQRSEGR DHVIPVHHPW 240 SFKSVRSFVK KAIWLLPDMD STGNWYKPGQ VYLEKDVILP YVPNVDLCDS KCVSETQSKR 300 SILLFFRGRL KRNAGGKIRS KLVEELKGAE GIVIEEGSAG AQGKTAAQDG MRKSLFCLSP 360 AGDTPSSARL FDAIVSGCIP VIISDELELP FEGILDYREI ALFVSSTDAL QPGWLMNYLR 420 RIDAKRIREM QSNLVKFSRH FLYSSPAQPL GPEDLTWRMI AGKLLNIKLH IRRSQRVVRE 480 SRSICTCECR VGNTTRML* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-73 | 112 | 422 | 319 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAF06505.2 | 0 | 43 | 483 | 44 | 484 | Os01g0811400 [Oryza sativa Japonica Group] |
GenBank | EAY76230.1 | 0 | 43 | 486 | 45 | 488 | hypothetical protein OsI_04166 [Oryza sativa Indica Group] |
RefSeq | NP_001044591.1 | 0 | 43 | 486 | 44 | 487 | Os01g0811400 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001141657.1 | 0 | 1 | 498 | 1 | 497 | hypothetical protein LOC100273782 [Zea mays] |
RefSeq | XP_002458661.1 | 0 | 1 | 498 | 1 | 499 | hypothetical protein SORBIDRAFT_03g037670 [Sorghum bicolor] |