| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si002419m |
| Family | GH18 |
| Protein Properties | Length: 296 Molecular Weight: 30536.9 Isoelectric Point: 4.1065 |
| Chromosome | Chromosome/Scaffold: 5 Start: 31453199 End: 31454436 |
| Description | chitinase A |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 26 | 244 | 1.3e-29 |
| GNIAVYWGQNGGEGSLADACNSGNYAYVIIAFLSTFGNGQTPVLNLAGHCDPSSPGSCTFLSSEIQTCKSQGIKVLLSLGGGGGNYGLSSTDDANSVANY LWDYYLGGSGSPRPLGDAALDGIDFDIENGNSAHYDDLANALKAKGSVMLTAAPQCPYPDASLGPALQTGQFDNVWIQFYNNPGCSYANGDDTNLVNAWR TWTSSVTAGSFYLGLPASN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 296 Download |
| MAANLKWPPV LALLLVAGMA GIASAGNIAV YWGQNGGEGS LADACNSGNY AYVIIAFLST 60 FGNGQTPVLN LAGHCDPSSP GSCTFLSSEI QTCKSQGIKV LLSLGGGGGN YGLSSTDDAN 120 SVANYLWDYY LGGSGSPRPL GDAALDGIDF DIENGNSAHY DDLANALKAK GSVMLTAAPQ 180 CPYPDASLGP ALQTGQFDNV WIQFYNNPGC SYANGDDTNL VNAWRTWTSS VTAGSFYLGL 240 PASNDAAGSG YIAPGDLTGK VIPDIQSIGS YGGIMLWSRF YDVQKNYSGQ VKGSV* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG3469 | COG3469 | 4.0e-6 | 146 | 289 | 180 | + Chitinase [Carbohydrate transport and metabolism] | ||
| cd02871 | GH18_chitinase_D-like | 1.0e-6 | 31 | 288 | 313 | + GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus. | ||
| pfam00704 | Glyco_hydro_18 | 1.0e-17 | 26 | 244 | 250 | + Glycosyl hydrolases family 18. | ||
| cd02877 | GH18_hevamine_XipI_class_III | 9.0e-122 | 26 | 293 | 280 | + This conserved domain family includes xylanase inhibitor Xip-I, and the class III plant chitinases such as hevamine, concanavalin B, and PPL2, all of which have a glycosyl hydrolase family 18 (GH18) domain. Hevamine is a class III endochitinase that hydrolyzes the linear polysaccharide chains of chitin and peptidoglycan and is important for defense against pathogenic bacteria and fungi. PPL2 (Parkia platycephala lectin 2) is a class III chitinase from Parkia platycephala seeds that hydrolyzes beta(1-4) glycosidic bonds linking 2-acetoamido-2-deoxy-beta-D-glucopyranose units in chitin. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABW75909.1 | 0 | 1 | 295 | 1 | 299 | class III chitinase [Bambusa oldhamii] |
| GenBank | ACF88326.1 | 0 | 26 | 295 | 27 | 295 | unknown [Zea mays] |
| RefSeq | NP_001043772.1 | 0 | 1 | 295 | 1 | 301 | Os01g0660200 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001105541.1 | 0 | 26 | 295 | 27 | 294 | chitinase chem5 [Zea mays] |
| RefSeq | XP_002456083.1 | 0 | 1 | 295 | 1 | 295 | hypothetical protein SORBIDRAFT_03g030100 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2gsj_A | 0 | 26 | 295 | 1 | 271 | A Chain A, Cdna Cloning And 1.75a Crystal Structure Determination Of Ppl2, A Novel Chimerolectin From Parkia Platycephala Seeds Exhibiting Endochitinolytic Activity |
| PDB | 2hvm_A | 0 | 26 | 295 | 1 | 273 | A Chain A, Cdna Cloning And 1.75a Crystal Structure Determination Of Ppl2, A Novel Chimerolectin From Parkia Platycephala Seeds Exhibiting Endochitinolytic Activity |
| PDB | 1llo_A | 0 | 26 | 295 | 1 | 273 | A Chain A, Cdna Cloning And 1.75a Crystal Structure Determination Of Ppl2, A Novel Chimerolectin From Parkia Platycephala Seeds Exhibiting Endochitinolytic Activity |
| PDB | 1hvq_A | 0 | 26 | 295 | 1 | 273 | A Chain A, Crystal Structures Of Hevamine, A Plant Defence Protein With Chitinase And Lysozyme Activity, And Its Complex With An Inhibitor |
| PDB | 1kr0_A | 0 | 26 | 295 | 1 | 273 | A Chain A, Hevamine Mutant D125aY183F IN COMPLEX WITH TETRA-Nag |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
