Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si004108m |
Family | GT47 |
Protein Properties | Length: 522 Molecular Weight: 59107 Isoelectric Point: 9.2103 |
Chromosome | Chromosome/Scaffold: 5 Start: 6189641 End: 6193110 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 186 | 472 | 0 |
KLLKVFIYHDGAKPIFHSPELKGIYASEGWFMKLMETNQNFVVRDPNRAHLFYLPYSSRQLEHNLYVPGSNTIEPLSIFVKNYIDMISAKYPYWNRTKGA DHFFVACHDWGPYTTKLHDELRKNTIKALCNADLSEGVFVRGKDVSLPETFLRAPRRPLRDIGGRPVAQRTILAFFAGQMHGRVRPVLLKYWGDKDPDMR IYSKLPHRITRRRNYVQHMKSSKYCICPMGYEVNSPRIVEAIYYECVPVIIADNFVLPFDDALNWSSFSVVVAERDVPKLKDILLGI |
Full Sequence |
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Protein Sequence Length: 522 Download |
MPHHATPQHA STARKFLSRP RVVAACAAVA ALALFLAASS AAEDPSRWRA YLMRPLPGGA 60 REETVVAAAV AGSFAGPAAS SPSPAEAPLP SLGETNLSGR IDPIPATSMF LVPSSSPAEN 120 FDDGSMEERE RPEIKAPLWS TAADDELVYV KKEIINAPLT SDDPDLYAPL FRNVSVFKRS 180 YELMEKLLKV FIYHDGAKPI FHSPELKGIY ASEGWFMKLM ETNQNFVVRD PNRAHLFYLP 240 YSSRQLEHNL YVPGSNTIEP LSIFVKNYID MISAKYPYWN RTKGADHFFV ACHDWGPYTT 300 KLHDELRKNT IKALCNADLS EGVFVRGKDV SLPETFLRAP RRPLRDIGGR PVAQRTILAF 360 FAGQMHGRVR PVLLKYWGDK DPDMRIYSKL PHRITRRRNY VQHMKSSKYC ICPMGYEVNS 420 PRIVEAIYYE CVPVIIADNF VLPFDDALNW SSFSVVVAER DVPKLKDILL GIPESRYITL 480 QSNVKRVQKH FLWHPNPVKY DIFHMILHSV WFSRVNQMRI E* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-68 | 184 | 472 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 138 | 520 | 153 | 535 | unnamed protein product [Vitis vinifera] |
GenBank | EEC69788.1 | 0 | 79 | 521 | 59 | 536 | hypothetical protein OsI_00072 [Oryza sativa Indica Group] |
RefSeq | NP_001041784.1 | 0 | 81 | 521 | 62 | 550 | Os01g0107700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002269459.1 | 0 | 138 | 520 | 153 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002457517.1 | 0 | 3 | 519 | 5 | 521 | hypothetical protein SORBIDRAFT_03g008610 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |