Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si004162m |
Family | GT47 |
Protein Properties | Length: 509 Molecular Weight: 57445.4 Isoelectric Point: 10.3438 |
Chromosome | Chromosome/Scaffold: 5 Start: 30355625 End: 30357618 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 171 | 458 | 0 |
RILKVYIYQDGRRPIFHTPPLSGIYASEGWFMKLLKESRRHVVADPSKAHLFYLPYSSQQLRLTLYVPDSHDLRPLSVYLRNFVRGLANKYPFWNRTRGA DHFLVACHDWGPYTATSHRDLRKNAIKALCNADSSEGIFTPGKDVSLPETTIRTPRRPLRYVGGLPVSRRGILAFFAGNVHGRVRPELLRHWGDGRDDDM RVYSLLPSRVSRRMSYIQHMKNSRFCLCPMGYEVNSPRIVEALYYECVPVIIADNFVLPLSEVLDWSAFSVVVAEKDIPDLKRILQGI |
Full Sequence |
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Protein Sequence Length: 509 Download |
MRPPPHLAAP SAAAPSSAAS HTGPSRRRHR HRGATTTSSV ACCRVAALAC LLAAGAATAL 60 LTLSLPSTPG ASTTTTTDFT VRLSVANQPP PPTHLPAPLA PATPPPPPPS PPAVRRRKRE 120 PSYWRMAPEE ALRYAKREIR DAEPALDDPD LYAPLFKNVS QFKRSYELME RILKVYIYQD 180 GRRPIFHTPP LSGIYASEGW FMKLLKESRR HVVADPSKAH LFYLPYSSQQ LRLTLYVPDS 240 HDLRPLSVYL RNFVRGLANK YPFWNRTRGA DHFLVACHDW GPYTATSHRD LRKNAIKALC 300 NADSSEGIFT PGKDVSLPET TIRTPRRPLR YVGGLPVSRR GILAFFAGNV HGRVRPELLR 360 HWGDGRDDDM RVYSLLPSRV SRRMSYIQHM KNSRFCLCPM GYEVNSPRIV EALYYECVPV 420 IIADNFVLPL SEVLDWSAFS VVVAEKDIPD LKRILQGIPL RRYVAMHGCV KRLQRHFLWH 480 ARPIKYDLFH MILHSIWLSR VNQVELDG* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-70 | 173 | 458 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EEC71161.1 | 0 | 3 | 506 | 2 | 497 | hypothetical protein OsI_03019 [Oryza sativa Indica Group] |
GenBank | EEE55063.1 | 0 | 3 | 506 | 2 | 480 | hypothetical protein OsJ_02778 [Oryza sativa Japonica Group] |
RefSeq | NP_001043679.1 | 0 | 3 | 506 | 2 | 499 | Os01g0640600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002269459.1 | 0 | 124 | 506 | 154 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002456034.1 | 0 | 1 | 508 | 1 | 517 | hypothetical protein SORBIDRAFT_03g029210 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
GT051299 | 334 | 160 | 493 | 0 |
BX834842 | 335 | 170 | 503 | 0 |
CF439188 | 277 | 174 | 449 | 0 |
ES808098 | 348 | 138 | 485 | 0 |
DT597828 | 264 | 127 | 390 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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