Basic Information | |
---|---|
Species | Setaria italica |
Cazyme ID | Si009874m |
Family | GH29 |
Protein Properties | Length: 512 Molecular Weight: 56533.9 Isoelectric Point: 5.1578 |
Chromosome | Chromosome/Scaffold: 7 Start: 27030570 End: 27034193 |
Description | alpha-L-fucosidase 1 |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GH29 | 38 | 335 | 0 |
YAQLRWQLSEMALFLHFGPNTFTDSEWGTGRADPSVFAPSALDAGQWARVAARAGFRRVVLTAKHHDGFCLWPSALTNYSVAASPWRGGAGDVVAELAAA ARAEGVGLGLYLSPWDRHEPVYGDTVPYNEHYMGQMTELLTRYGEVEEVWLDGAKGDAKKMDYMFDAWFSLIHQLQQRVVIFSDAGPDTRWVGDEVGVAG YTCWSTFNKSSVTIGHTIAEYSRCGDPYGQDWVPAECDVSIRPGWFWHASEKPKNATTLLDIYYKSVGRNCLLILNVPPNSSGLISDEDMQVLQEFTE |
Full Sequence |
---|
Protein Sequence Length: 512 Download |
MAALLPVLLA HLLLCAHGAT ASAAATPPPL PILPVPSYAQ LRWQLSEMAL FLHFGPNTFT 60 DSEWGTGRAD PSVFAPSALD AGQWARVAAR AGFRRVVLTA KHHDGFCLWP SALTNYSVAA 120 SPWRGGAGDV VAELAAAARA EGVGLGLYLS PWDRHEPVYG DTVPYNEHYM GQMTELLTRY 180 GEVEEVWLDG AKGDAKKMDY MFDAWFSLIH QLQQRVVIFS DAGPDTRWVG DEVGVAGYTC 240 WSTFNKSSVT IGHTIAEYSR CGDPYGQDWV PAECDVSIRP GWFWHASEKP KNATTLLDIY 300 YKSVGRNCLL ILNVPPNSSG LISDEDMQVL QEFTEIRHTI FSHNFAANAT VTANSVRGGQ 360 DNLQFAPSNV LEDSIYSYWA PQEGQTCWEM LFDLGQSASF NVLQLQEPIQ LGQRVIEFHV 420 DILIDELWQT IVEATTIGYK RLLKFPVTES RYLKLSINSA RADPLISFFG VFMDSFSGKY 480 NLENHNKRTN SSEVIMLRTG SAAGNRSTAA M* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01120 | Alpha_L_fucos | 3.0e-17 | 74 | 335 | 276 | + Alpha-L-fucosidase. | ||
smart00812 | Alpha_L_fucos | 3.0e-18 | 74 | 335 | 283 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
COG3669 | COG3669 | 5.0e-48 | 40 | 472 | 446 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0004560 | alpha-L-fucosidase activity |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACG47369.1 | 0 | 15 | 511 | 15 | 513 | alpha-L-fucosidase 1 precursor [Zea mays] |
EMBL | CAH68057.1 | 0 | 16 | 511 | 20 | 517 | B0103C08-B0602B01.14 [Oryza sativa (indica cultivar-group)] |
RefSeq | NP_001053546.1 | 0 | 16 | 511 | 20 | 517 | Os04g0560400 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001131532.1 | 0 | 15 | 511 | 15 | 513 | hypothetical protein LOC100192871 [Zea mays] |
RefSeq | XP_002448322.1 | 0 | 17 | 511 | 17 | 513 | hypothetical protein SORBIDRAFT_06g025200 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3mo4_B | 0 | 36 | 467 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
PDB | 3mo4_A | 0 | 36 | 467 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
PDB | 3ues_B | 0 | 36 | 467 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3ues_A | 0 | 36 | 467 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3eyp_B | 0 | 31 | 475 | 5 | 457 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |