| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si012681m |
| Family | AA7 |
| Protein Properties | Length: 500 Molecular Weight: 56013.7 Isoelectric Point: 7.8765 |
| Chromosome | Chromosome/Scaffold: 7 Start: 8916339 End: 8917838 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 39 | 491 | 0 |
| LRYVLPGTVRPLVIVAVTEPGHVQTTVLCGRRHSVRIRTRSGGHDYEGLSYASLDPHQRFAVLDLAELRAIHIDAARAEAWVGSGASLGELYYAVAAANR TLAFPAGSCPTVCFGGHLSGGGFGSLARKYGLSADNVLDAVVVDAQGRLLNRSTMGEDFFWAIRGGGGESFGVVVSWKVRLVRVPETVTVFGIRRFRNQS AIDLVTKWQDIAPFLPRDLYLRVLVQNPQADFVALFLGRCGRLFDIMRRRFPELGMTQADCQEISWVQSTIFIEFFTTDKPLEVLLDRSNKPDYYLKVKS DHVQEPIPRHAWESLWEKWLDEPGTPPIMLDPYGGRMGSISPSATPFPHRDYLYQLQIYSFWFENGTDALEKRISWVRGVHKELEPYVSKNPRAVYVNYR DLDLGTNELEGNVTSYDNAKVWGEKYFKGNFERLAGVKSRVDPDDFFRNEQSI | |||
| Full Sequence |
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| Protein Sequence Length: 500 Download |
| SSDVDAFLGC LYADIPPRLV HTPSTNNYSA LLLSSVRNLR YVLPGTVRPL VIVAVTEPGH 60 VQTTVLCGRR HSVRIRTRSG GHDYEGLSYA SLDPHQRFAV LDLAELRAIH IDAARAEAWV 120 GSGASLGELY YAVAAANRTL AFPAGSCPTV CFGGHLSGGG FGSLARKYGL SADNVLDAVV 180 VDAQGRLLNR STMGEDFFWA IRGGGGESFG VVVSWKVRLV RVPETVTVFG IRRFRNQSAI 240 DLVTKWQDIA PFLPRDLYLR VLVQNPQADF VALFLGRCGR LFDIMRRRFP ELGMTQADCQ 300 EISWVQSTIF IEFFTTDKPL EVLLDRSNKP DYYLKVKSDH VQEPIPRHAW ESLWEKWLDE 360 PGTPPIMLDP YGGRMGSISP SATPFPHRDY LYQLQIYSFW FENGTDALEK RISWVRGVHK 420 ELEPYVSKNP RAVYVNYRDL DLGTNELEGN VTSYDNAKVW GEKYFKGNFE RLAGVKSRVD 480 PDDFFRNEQS IPPLRAAKG* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 8.0e-7 | 45 | 200 | 163 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 6.0e-16 | 49 | 191 | 144 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| pfam08031 | BBE | 1.0e-17 | 433 | 492 | 60 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD54128.1 | 0 | 1 | 499 | 32 | 531 | putative CPRD2 [Oryza sativa Japonica Group] |
| GenBank | EAZ01285.1 | 0 | 1 | 499 | 32 | 496 | hypothetical protein OsI_23309 [Oryza sativa Indica Group] |
| RefSeq | NP_001057826.1 | 0 | 1 | 499 | 1243 | 1742 | Os06g0548100 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001143977.1 | 0 | 4 | 499 | 31 | 527 | hypothetical protein LOC100276794 [Zea mays] |
| RefSeq | XP_002443690.1 | 0 | 17 | 497 | 16 | 511 | hypothetical protein SORBIDRAFT_07g000490 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3tsj_B | 0 | 7 | 494 | 11 | 496 | A Chain A, Structure Of Ugt78g1 Complexed With Myricetin And Udp |
| PDB | 3tsj_A | 0 | 7 | 494 | 11 | 496 | A Chain A, Structure Of Ugt78g1 Complexed With Myricetin And Udp |
| PDB | 3tsh_A | 0 | 7 | 494 | 11 | 496 | A Chain A, Crystal Structure Of Phl P 4, A Grass Pollen Allergen With Glucose Dehydrogenase Activity |
| PDB | 4dns_B | 0 | 7 | 494 | 13 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 7 | 494 | 13 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HX127313 | 261 | 239 | 497 | 0 |
| DR973344 | 248 | 223 | 469 | 0 |
| FF362497 | 228 | 272 | 498 | 0 |
| HO777438 | 512 | 5 | 494 | 0 |
| HX201224 | 240 | 227 | 464 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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