Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si013243m |
Family | GT20 |
Protein Properties | Length: 864 Molecular Weight: 98119.7 Isoelectric Point: 6.5706 |
Chromosome | Chromosome/Scaffold: 6 Start: 25791512 End: 25797106 |
Description | trehalose-phosphatase/synthase 9 |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 55 | 544 | 0 |
SFSERKIIVANFLPLNCTRDEAGQLSFSLDDDALLVQLKHGFSNETDVVYVGSLKIQVDPSEQDQVAQKLLREYRCIPTFLPSDLQQQFYHGFCKQQLWP LFHYMLPICLDKGELFDRSLFQAYVRANKLFADKVMEVINTDDDYVWVHDYHLMLLPTFLRKRLHRIKLGFFLHSPFPSSEIYRTLPVRDEILKSLLNAD LIGFQTFDYARHFLSCCSRLLGLHYESKRGYIGIEYFGRTVSLKILSVGVHVGRLESVLNLPATVSKVQEIEQRYKGKMLMLGVDDMDIFKGISLKLLGL ELLLERNPKLRQKVVLVQIINPARSTGKDVQEAITETVSVAERINRKYGSSGYNPVVLIDHHIPFYEKIAFYAASDCCIVNAVRDGMNLVPYEYTVCRQG NEEIDKLRGFDKDTSHTSTLIVSEFVGCSPSLSGAFRVNPWSVDDVADALCHATDLTESEKRLRHEKHYRYVSTHDVAYWARSFAQDLER |
Full Sequence |
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Protein Sequence Length: 864 Download |
MVSKSYSNLL DMTSGDGFDF RQPFKSLPRV VTSPGIISDP DWDTRSDDDS VGSASFSERK 60 IIVANFLPLN CTRDEAGQLS FSLDDDALLV QLKHGFSNET DVVYVGSLKI QVDPSEQDQV 120 AQKLLREYRC IPTFLPSDLQ QQFYHGFCKQ QLWPLFHYML PICLDKGELF DRSLFQAYVR 180 ANKLFADKVM EVINTDDDYV WVHDYHLMLL PTFLRKRLHR IKLGFFLHSP FPSSEIYRTL 240 PVRDEILKSL LNADLIGFQT FDYARHFLSC CSRLLGLHYE SKRGYIGIEY FGRTVSLKIL 300 SVGVHVGRLE SVLNLPATVS KVQEIEQRYK GKMLMLGVDD MDIFKGISLK LLGLELLLER 360 NPKLRQKVVL VQIINPARST GKDVQEAITE TVSVAERINR KYGSSGYNPV VLIDHHIPFY 420 EKIAFYAASD CCIVNAVRDG MNLVPYEYTV CRQGNEEIDK LRGFDKDTSH TSTLIVSEFV 480 GCSPSLSGAF RVNPWSVDDV ADALCHATDL TESEKRLRHE KHYRYVSTHD VAYWARSFAQ 540 DLERACKDHY SRRCWAIGFG LNFRVIALSP GFRKLSSEHF VSCYNKASRR AIFLDYDGTL 600 VPQSSINKAP SAEVISILKT LCNDPKNNVF IVSGRGRDSL DEWFSPCEKL GIAAEHGYFV 660 RWSKEAEWES SYPRTQREWK HIAEPVMKVY TETTDGSSIE PKESALVWHY LDADHDFGSC 720 QAKELQDHLE RVLSNEPVVV KCGHYIVEVK PQGVSKGLAV DKLIRSLVNN GKAPDFLMCI 780 GNDRSDEDMF ESINGMTSNT VLSPTVPEVF ACSVGQKPSK AKYYVDDTTE VIRLLKNVTR 840 SSSQREDVSH GRVTFRDVID FVE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 5.0e-157 | 59 | 836 | 812 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 1 | 844 | 851 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 58 | 544 | 491 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 59 | 841 | 790 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 0 | 61 | 543 | 483 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EEC83577.1 | 0 | 1 | 863 | 1 | 862 | hypothetical protein OsI_29236 [Oryza sativa Indica Group] |
GenBank | EEE68684.1 | 0 | 1 | 844 | 1 | 843 | hypothetical protein OsJ_27312 [Oryza sativa Japonica Group] |
RefSeq | NP_001061805.1 | 0 | 1 | 863 | 1 | 862 | Os08g0414700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002445486.1 | 0 | 1 | 863 | 1 | 865 | hypothetical protein SORBIDRAFT_07g020270 [Sorghum bicolor] |
RefSeq | XP_002462305.1 | 0 | 1 | 862 | 1 | 860 | hypothetical protein SORBIDRAFT_02g023610 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 142 | 544 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 142 | 544 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 142 | 544 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 142 | 544 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1gz5_D | 0 | 142 | 544 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 771 | 80 | 844 | 0 |
HO779327 | 522 | 90 | 611 | 0 |
HO779327 | 254 | 607 | 859 | 0 |
HO797286 | 470 | 375 | 844 | 0 |
HO777775 | 75 | 1 | 73 | 0.27 |
Sequence Alignments (This image is cropped. Click for full image.) |
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