Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si015706m |
Family | GT47 |
Protein Properties | Length: 503 Molecular Weight: 55972.2 Isoelectric Point: 10.0361 |
Chromosome | Chromosome/Scaffold: 6 Start: 28415782 End: 28417375 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 119 | 440 | 0 |
ALRVYVYDLPAEFHFGMLGWDGGKGRLAAAWPDVGDARAAPHYPGGLNLQHSVAYWLLLDILSSSTPPPGRPCVAVRVANASLADVFFVPFFASLSYNRH SKLRRGEKVSRNRALQAELVKYLSRKEEWRRWGGRDHLIVPHHPNSMMEARKRLSAAMFVLSDFGRYSPDVANLKKDVIAPYKHVVRSLADDESPAFDQR PVLAYFQGAIHRKAGGKVRQKLYQLLKDERDVHFTYGSVRRDGIRRATAGMSTSKFCLNIAGDTPSSNRLFDAIASHCVPVIVSDDIELPFEDVLDYSEF CVFVRAADAARKGFLLRLLRGI |
Full Sequence |
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Protein Sequence Length: 503 Download |
MVLERKMQPP LPPPEHRRAL RFVVFLAVSL LAFSCWALVN SRINDAIPDS AVLVRDADDK 60 TAPALTGDDP AAAVPVGGAA TARAANLSDP VIRVPPLVRG GGGEGEQRIS ERCDADLAAL 120 RVYVYDLPAE FHFGMLGWDG GKGRLAAAWP DVGDARAAPH YPGGLNLQHS VAYWLLLDIL 180 SSSTPPPGRP CVAVRVANAS LADVFFVPFF ASLSYNRHSK LRRGEKVSRN RALQAELVKY 240 LSRKEEWRRW GGRDHLIVPH HPNSMMEARK RLSAAMFVLS DFGRYSPDVA NLKKDVIAPY 300 KHVVRSLADD ESPAFDQRPV LAYFQGAIHR KAGGKVRQKL YQLLKDERDV HFTYGSVRRD 360 GIRRATAGMS TSKFCLNIAG DTPSSNRLFD AIASHCVPVI VSDDIELPFE DVLDYSEFCV 420 FVRAADAARK GFLLRLLRGI SREEWTRMWG RLKEVARHFE YQYPSRPGDA VQMIWGAVAR 480 KMHSVKLQLH KRGRYQRTGS ES* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-61 | 120 | 435 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EEC83632.1 | 0 | 1 | 502 | 53 | 566 | hypothetical protein OsI_29363 [Oryza sativa Indica Group] |
RefSeq | NP_001061895.1 | 0 | 1 | 502 | 53 | 566 | Os08g0438600 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002284930.1 | 0 | 113 | 498 | 66 | 448 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 113 | 498 | 27 | 409 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002444408.1 | 0 | 4 | 502 | 8 | 539 | hypothetical protein SORBIDRAFT_07g021480 [Sorghum bicolor] |