| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si016067m |
| Family | GT48 |
| Protein Properties | Length: 1957 Molecular Weight: 225243 Isoelectric Point: 9.584 |
| Chromosome | Chromosome/Scaffold: 1 Start: 42017703 End: 42033495 |
| Description | glucan synthase-like 12 |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT48 | 1065 | 1812 | 0 |
| VPTNLDARRRISFFANSLFMSMPRAPKVRQMLPFSVLTPYYKEDVLFSSHALEEPNEDGVSILFYLQKIYPDEWNNFLQRVDCKNEEELRETEQSEEELR LWASYRGQTLTRTVRGMMYYRQALVLQAFLDMARDEDLMEGFRAADLLSDESQLLTQCKAIADMKFTYVVSCQQYGIQKRSGDPRAQDILRLMTTYPSLR VAYIDEVEEPSKDRNKKIEKVYYSALVKAAVTKPDDPGQKLDQDIYRIKLPGNAMLGEGKPENQNHAIIFTRGEGLQTIDMNQEHYMEETLKMRNLLQEF LKKHDGVRYPSILGVREHIFTGSVSSLAWFMSNQETSFVTIGQRVLANPLRVRFHYGHPDIFDRLFHLTRGGVSKASKIINLSEDIFAGFNSTLREGNVT HHEYMQVGKGRDVGLNQISLFEAKIANGNGEQTLSRDVYRLGHRFDFFRMLSCYYTTIGFYFSTMITVWTVYVFLYGRLYLVLSGLDEALATGKRFIHNE PLQVALASQSFVQLGFLMALPMMMEIGLERGFRTALSDFVLMQLQLASVFFTFSLGTKTHYYGTTLLHGGAEYRATGRGFVVFHAKFAENYRLYSRSHFV KGIELMILLIVYEIFGQSYRGAIAYIFITISMWFMVVTWLFAPFLFNPSGFEWQKIVDDWTDWNKWISNRGGIGVPPEKSWESWWEKEQEPLRLSGKRGI ILEIVLALRFFIYQYGLVYHLNITTHTKSVLVYCLSWVVIFVILLVMK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1957 Download |
| MASSSGGRRM APGGDSSSAS PASAGAGAGP RRILRTQTAG NLGESIFDSE VVPSSLVEIA 60 PILRVANEVE ASNPRVAYLC RFYAFEKAHR LDPTSSGRGV RQFKTALLQR LERENDPTLK 120 GRVKQSDARE MQSFYQHYYK KYIQALQNAA DKADRAQLTK AYQTAAVLFE VLKAVNVSQK 180 IEVDQSILET HNQVEEKKKL YLPYNILPLD PDSANQAIMR YPEIQAAFHA LRNTRGLPWP 240 KEHEKKPDAD LLGWLQAMFG FQKDNVSNQR EHLILLLANV HIRQIPKPDQ QPKLDDRALD 300 TVMKKLFKNY KKWCKYLGRK SSLWLPTIQQ EVQQRKLLYM GLYLLIWGEA ANLRFMPECL 360 CYIYHHMAFE LYGMLAGNVS PTTGENVKPA YGGEEEAFLK KVVTPIYKVI EKEAERSKIV 420 KSKHSHWRNY DDLNEYFWSR DCFRLGWPMR ADADFFKTPN DDRRHPVNGE DRPVANGNWM 480 GKVNFVEVRS FWHIFRSFDR MWSFLILSLQ AMIIIAWNGG TPSDIFDRGV FKQVLSIFIT 540 AAILKLGQAI LDIILSWKAR KNMSLVVKLR YILKLLSAAA WVVILPVTYA YTWQNPTGLA 600 RTIKSWLGDG QNQPSLYILA VVVYLAPNIL SAVLFLFPVI RRALERSNLK VVTFMMWWSQ 660 PRLFVGRGMH EGAFSLFKYT MFWVLLLATK LVVSFYVEIK PLVQPTQDIM KEPIRTFKWH 720 EFFPHANNNI GVVIALWAPI ILVYFMDTQI WYAIFSTIVG GIYGACRRLG EIRTLGMLRS 780 RFESLPKAFN QCLIPSDTSK RRGFRAAFSS KPSKTPEGTK EEEKIAARFA QIWNLIITSF 840 REEDLINNRE KDLLLVPYCK DRDMDIIQWP PFLLASKIPI ALDMAADSGG KDRDLKKRMK 900 SDPYFTYAIK ECYASFKNII YALVIGPRER DVIQKIFDVV DEHIAGDTLI TELNMSNLPT 960 LSKKFIELLD LLQKNNIEDQ GQVIILFQDM LEVVTRDIMD EQLSGLLESI HGGNNRRYEG 1020 ITPLDQQVQL FTKAIDFPVK ETQAWTEKIK RLHLLLTVKE SAMDVPTNLD ARRRISFFAN 1080 SLFMSMPRAP KVRQMLPFSV LTPYYKEDVL FSSHALEEPN EDGVSILFYL QKIYPDEWNN 1140 FLQRVDCKNE EELRETEQSE EELRLWASYR GQTLTRTVRG MMYYRQALVL QAFLDMARDE 1200 DLMEGFRAAD LLSDESQLLT QCKAIADMKF TYVVSCQQYG IQKRSGDPRA QDILRLMTTY 1260 PSLRVAYIDE VEEPSKDRNK KIEKVYYSAL VKAAVTKPDD PGQKLDQDIY RIKLPGNAML 1320 GEGKPENQNH AIIFTRGEGL QTIDMNQEHY MEETLKMRNL LQEFLKKHDG VRYPSILGVR 1380 EHIFTGSVSS LAWFMSNQET SFVTIGQRVL ANPLRVRFHY GHPDIFDRLF HLTRGGVSKA 1440 SKIINLSEDI FAGFNSTLRE GNVTHHEYMQ VGKGRDVGLN QISLFEAKIA NGNGEQTLSR 1500 DVYRLGHRFD FFRMLSCYYT TIGFYFSTMI TVWTVYVFLY GRLYLVLSGL DEALATGKRF 1560 IHNEPLQVAL ASQSFVQLGF LMALPMMMEI GLERGFRTAL SDFVLMQLQL ASVFFTFSLG 1620 TKTHYYGTTL LHGGAEYRAT GRGFVVFHAK FAENYRLYSR SHFVKGIELM ILLIVYEIFG 1680 QSYRGAIAYI FITISMWFMV VTWLFAPFLF NPSGFEWQKI VDDWTDWNKW ISNRGGIGVP 1740 PEKSWESWWE KEQEPLRLSG KRGIILEIVL ALRFFIYQYG LVYHLNITTH TKSVLVYCLS 1800 WVVIFVILLV MKTVSVGRRR FSAEFQLVFR LIKGLIFITF ISIIIILIAI PHMTVQDMFV 1860 CILAFMPTGW GLLLIARAIK PAITKFQLWG SIKALARGYE IIMGLLLFTP IAFLAWFPFV 1920 SEFQTRMLFN QAFSRGLQIS RILGGHKKDR ATRNKE* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04652 | DUF605 | 5.0e-11 | 59 | 173 | 120 | + Vta1 like. Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. | ||
| pfam14288 | FKS1_dom1 | 7.0e-57 | 334 | 450 | 118 | + 1,3-beta-glucan synthase subunit FKS1, domain-1. The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364. | ||
| pfam02364 | Glucan_synthase | 0 | 1065 | 1808 | 818 | + 1,3-beta-glucan synthase component. This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000148 | 1,3-beta-D-glucan synthase complex |
| GO:0003843 | 1,3-beta-D-glucan synthase activity |
| GO:0006075 | (1->3)-beta-D-glucan biosynthetic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD23015.1 | 0 | 31 | 1956 | 35 | 1969 | putative callose synthase 1 catalytic subunit [Oryza sativa Japonica Group] |
| DDBJ | BAD62105.1 | 0 | 31 | 1956 | 28 | 1959 | putative callose synthase 1 catalytic subunit [Oryza sativa Japonica Group] |
| GenBank | EEE58116.1 | 0 | 31 | 1956 | 35 | 1918 | hypothetical protein OsJ_09005 [Oryza sativa Japonica Group] |
| RefSeq | XP_002439067.1 | 0 | 31 | 1956 | 30 | 1965 | hypothetical protein SORBIDRAFT_10g030970 [Sorghum bicolor] |
| RefSeq | XP_002453103.1 | 0 | 8 | 1956 | 11 | 1942 | hypothetical protein SORBIDRAFT_04g038510 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2lxm_A | 0.002 | 63 | 172 | 21 | 128 | B Chain B, Lip5-chmp5 |
| PDB | 2lxl_A | 0.004 | 63 | 172 | 21 | 128 | A Chain A, Lip5(mit)2 |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| callose biosynthesis | 13-BETA-GLUCAN-SYNTHASE-RXN | EC-2.4.1.34 | 1,3-β-glucan synthase |
