| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si016360m |
| Family | GT20 |
| Protein Properties | Length: 786 Molecular Weight: 87659.3 Isoelectric Point: 7.6561 |
| Chromosome | Chromosome/Scaffold: 1 Start: 40169401 End: 40173735 |
| Description | trehalose phosphatase/synthase 11 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT20 | 48 | 531 | 0 |
| RRVIVSHRLPLRAAPDPAAPFGFAFTVDAGTVAYQLRSGLPASAPVLHIGTLPAAAAEAASDELSNYLLANFSCLPVYLPSDLHHRFYHGFCKHYLWPLL HYLLPLTPSSLGGLPFQRTLYHSFLSANRAFADRLTEVLSPDEDLVWIHDYHLLALPTFLRKRFPRAKVGFFLHSPFPSSEIFRTIPVRDDLVRALLNAD LVGFHTFDYARHFLSACSRLLGLDYQSKRGYIGIEYYGRTVTVKILPVGIDMGQLRSVVSAPETGDVVRRVAEAYKGRRLMIGVDDVDLFKGIGLKFLAM EQLLVEHPELRGRAVLVQIANPARSEGRDVQGVQDEAKAISARVNARFGTPGYTPIVLIDGPLTAHEKAAYYAAAECCVVSAVRDGLNRIPYIYTVCRQE SNALGEDSPKRSVIVLSEFVGCSPSLSGAIRVNPWSVESVAEAMNAALRMPEAEQRLRHEKHYKYVSTHDVAYWARSFDQDLQR | |||
| Full Sequence |
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| Protein Sequence Length: 786 Download |
| MPSLSCHNLL DLAAADEVPL PSPTPLRLPR VMSVASPASP TSPPTPPRRV IVSHRLPLRA 60 APDPAAPFGF AFTVDAGTVA YQLRSGLPAS APVLHIGTLP AAAAEAASDE LSNYLLANFS 120 CLPVYLPSDL HHRFYHGFCK HYLWPLLHYL LPLTPSSLGG LPFQRTLYHS FLSANRAFAD 180 RLTEVLSPDE DLVWIHDYHL LALPTFLRKR FPRAKVGFFL HSPFPSSEIF RTIPVRDDLV 240 RALLNADLVG FHTFDYARHF LSACSRLLGL DYQSKRGYIG IEYYGRTVTV KILPVGIDMG 300 QLRSVVSAPE TGDVVRRVAE AYKGRRLMIG VDDVDLFKGI GLKFLAMEQL LVEHPELRGR 360 AVLVQIANPA RSEGRDVQGV QDEAKAISAR VNARFGTPGY TPIVLIDGPL TAHEKAAYYA 420 AAECCVVSAV RDGLNRIPYI YTVCRQESNA LGEDSPKRSV IVLSEFVGCS PSLSGAIRVN 480 PWSVESVAEA MNAALRMPEA EQRLRHEKHY KYVSTHDVAY WARSFDQDLQ RACKDHFSRR 540 HWGIGFGMSF KVVALGPNFR RLSVEHIVPS YRRTENRLIL LDYDGTVMPE NSIDKTPSSE 600 VISVLNRLCE DPKNRVFIVS GRGKDELSKW FAPCEKLGIA AEHGYFTRWS RDAPWETSVL 660 AADFDWKKTA EPVMQLYTGA TDGSYIEHKE SAIVWHHHEA DPDFGSCQAK ELLDHLENVL 720 ANEPVVVKRG QHIVEVNPQV RQTRACFPHA FSIIILLFVG CLVQFEDVYE TWRSTTRSFQ 780 TKGTG* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 1.0e-133 | 116 | 738 | 631 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PRK14501 | PRK14501 | 1.0e-155 | 108 | 739 | 640 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 2.0e-169 | 85 | 530 | 446 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| pfam00982 | Glyco_transf_20 | 3.0e-173 | 81 | 531 | 454 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PLN02205 | PLN02205 | 0 | 75 | 739 | 674 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD19111.1 | 0 | 1 | 740 | 1 | 741 | putative alpha,alpha-trehalose-phosphate synthase [Oryza sativa Japonica Group] |
| GenBank | EAY87814.1 | 0 | 1 | 739 | 1 | 740 | hypothetical protein OsI_09233 [Oryza sativa Indica Group] |
| RefSeq | NP_001148318.1 | 0 | 1 | 739 | 1 | 741 | LOC100281927 [Zea mays] |
| RefSeq | XP_002452959.1 | 0 | 1 | 739 | 1 | 741 | hypothetical protein SORBIDRAFT_04g035560 [Sorghum bicolor] |
| RefSeq | XP_002511428.1 | 0 | 1 | 779 | 1 | 802 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 48 | 531 | 2 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 48 | 531 | 2 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 48 | 531 | 2 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 48 | 531 | 2 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1uqu_B | 0 | 48 | 531 | 3 | 453 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HO777775 | 668 | 82 | 739 | 0 |
| HO779327 | 516 | 89 | 598 | 0 |
| HO779327 | 186 | 594 | 771 | 0 |
| CD436045 | 278 | 334 | 611 | 0 |
| EE158670 | 276 | 230 | 505 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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