Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si019424m |
Family | GT47 |
Protein Properties | Length: 475 Molecular Weight: 52902.6 Isoelectric Point: 9.7637 |
Chromosome | Chromosome/Scaffold: 1 Start: 30729513 End: 30731170 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 141 | 425 | 0 |
ERKFKIWTYREGEPPLAHLGPSADIYSIEGQFLEEMEDPRNPFAARHPGEAHAFLLPVSVCNLVRYIYRLNTTAYVAPMRRMLADYIDVVADRYPYWNRS RGADHVIVSCHDWAPLVSEGNRELYTNAIRVLCNANTSEGFIPRKDATLPEVNLADGILRGPTFGLPPENRTTLAFFAGGMHGHIRKALLGYWLGKKDPD MDVHEYLPAGQDYHALMARARFCLCPSGFEVASPRVVESVFSGCVPVIISDGYPPPFGDVLDWSKMSVAVPSARIPELKDILRGV |
Full Sequence |
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Protein Sequence Length: 475 Download |
MENGGGGGHR VAAIAVPLLA FALLAAAFLG GGGGAAESPA SRERRREHFL RHVPHEPQKA 60 SEASRTMSAG TQHAAGKVSV GPIEESLAWS RAAIRRAARE APATAADSAR RSFKDVGDAF 120 VPRGAIYRNP RAFHRSYLEM ERKFKIWTYR EGEPPLAHLG PSADIYSIEG QFLEEMEDPR 180 NPFAARHPGE AHAFLLPVSV CNLVRYIYRL NTTAYVAPMR RMLADYIDVV ADRYPYWNRS 240 RGADHVIVSC HDWAPLVSEG NRELYTNAIR VLCNANTSEG FIPRKDATLP EVNLADGILR 300 GPTFGLPPEN RTTLAFFAGG MHGHIRKALL GYWLGKKDPD MDVHEYLPAG QDYHALMARA 360 RFCLCPSGFE VASPRVVESV FSGCVPVIIS DGYPPPFGDV LDWSKMSVAV PSARIPELKD 420 ILRGVSERRY RVLRARVLQA QRHFVMHRPA RRFDMIHMVL HSIWLRRLNV RLPY* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-68 | 140 | 425 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAD19700.1 | 0 | 140 | 474 | 1 | 345 | exostosin-like protein [Oryza sativa Japonica Group] |
GenBank | EAY86665.1 | 0 | 44 | 474 | 40 | 482 | hypothetical protein OsI_08049 [Oryza sativa Indica Group] |
RefSeq | NP_197526.4 | 0 | 60 | 473 | 6 | 408 | catalytic [Arabidopsis thaliana] |
Swiss-Prot | Q3E9A4 | 0 | 60 | 473 | 64 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002454169.1 | 0 | 140 | 474 | 1 | 338 | hypothetical protein SORBIDRAFT_04g025885 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |