Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si019524m |
Family | GT20 |
Protein Properties | Length: 816 Molecular Weight: 88210.7 Isoelectric Point: 6.5063 |
Chromosome | Chromosome/Scaffold: 1 Start: 9625734 End: 9628477 |
Description | trehalose-6-phosphatase synthase S8 |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 28 | 509 | 0 |
ARRIVAAHRLPLRASPDPDSPFGFAFSLDPDAPSLQLSRGFSPAPVTYIGTLPASVESKIVPSDELNDYLMENFSCLPVHLDGGRHAEFYDGFCKRYLWP LLHYLLPFTVADAGNLYFDEAEYRAFIAANRQFADRVIQVLSPDDGDLVIVHDYHLWALPTFLRRKCPRAGVGLFLHTPFPSAEILSSVAVCDELLRGLL NADLVGFHTSYYAHQFVSCCWGLLGVSYNISSLHGGHVGINYHGRTVLVKTFTVGVDMGRLRATLASPEAAAKAKEIAEAYRGRVLMVGVDDVDPFKGVG LKLLALEKMLEADQDMRRRVVLVQINNPARSAGGDADDVRSEAAQIERRINRRFGDGGELVVAIDGPVPMWVKAAYYAAADCCVVTAVRDGLNRIPYFYT VCREEGARRGGAVVVSQFAGCAASLGGAIRVNPLDPAALADAMRAAVTMDAEERQARHSANYGYLRAHDVADWARSFDKALN |
Full Sequence |
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Protein Sequence Length: 816 Download |
MQGSSSSSCV NKPSLAPPVP GADGPPAARR IVAAHRLPLR ASPDPDSPFG FAFSLDPDAP 60 SLQLSRGFSP APVTYIGTLP ASVESKIVPS DELNDYLMEN FSCLPVHLDG GRHAEFYDGF 120 CKRYLWPLLH YLLPFTVADA GNLYFDEAEY RAFIAANRQF ADRVIQVLSP DDGDLVIVHD 180 YHLWALPTFL RRKCPRAGVG LFLHTPFPSA EILSSVAVCD ELLRGLLNAD LVGFHTSYYA 240 HQFVSCCWGL LGVSYNISSL HGGHVGINYH GRTVLVKTFT VGVDMGRLRA TLASPEAAAK 300 AKEIAEAYRG RVLMVGVDDV DPFKGVGLKL LALEKMLEAD QDMRRRVVLV QINNPARSAG 360 GDADDVRSEA AQIERRINRR FGDGGELVVA IDGPVPMWVK AAYYAAADCC VVTAVRDGLN 420 RIPYFYTVCR EEGARRGGAV VVSQFAGCAA SLGGAIRVNP LDPAALADAM RAAVTMDAEE 480 RQARHSANYG YLRAHDVADW ARSFDKALNL ACRDHAALLL VGFGLGLGYR AMALRPRFQA 540 LTAEHVRPSY RDAACRLILL DYDGTMVPEQ QDERKGAPDA GIVRLLNELC ADPKNVVFLV 600 SGRGKDQLAA WFASCEKLGI CAEHGYFTRW SKGDPWEVMN KQVVPGGTGS GWKAVAERVM 660 RQYMEATAGS YMETKEIALA WHYQNADPVV GPCQAKELHD HLVGLLADEP ASVAIGSQIV 720 EVNPQGVNKG VAVRGVLSAM SRRGVAAPDL ALCFGDGEAD EDMFEALARS GARLAAGARV 780 FACTVGKKAT EAAFYVEEPA DVVGLLRALA RCYSY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 7.0e-110 | 29 | 810 | 821 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
cd03788 | GT1_TPS | 6.0e-121 | 29 | 509 | 489 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
pfam00982 | Glyco_transf_20 | 8.0e-130 | 29 | 509 | 485 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 9.0e-137 | 76 | 812 | 746 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
PLN02205 | PLN02205 | 0 | 29 | 810 | 801 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EAY87814.1 | 0 | 16 | 810 | 36 | 827 | hypothetical protein OsI_09233 [Oryza sativa Indica Group] |
GenBank | EAZ07161.1 | 0 | 28 | 810 | 23 | 804 | hypothetical protein OsI_29408 [Oryza sativa Indica Group] |
GenBank | EAZ44803.1 | 0 | 29 | 810 | 48 | 857 | hypothetical protein OsJ_29437 [Oryza sativa Japonica Group] |
RefSeq | NP_001061925.1 | 0 | 28 | 810 | 23 | 804 | Os08g0445700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002452959.1 | 0 | 29 | 810 | 50 | 828 | hypothetical protein SORBIDRAFT_04g035560 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 3e-35 | 115 | 504 | 75 | 447 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 3e-35 | 115 | 504 | 75 | 447 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 3e-35 | 115 | 504 | 75 | 447 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 3e-35 | 115 | 504 | 75 | 447 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 3e-35 | 115 | 504 | 75 | 447 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 778 | 51 | 810 | 0 |
HO779327 | 514 | 69 | 569 | 0 |
HO779327 | 235 | 577 | 809 | 0 |
HO797286 | 470 | 354 | 810 | 0 |
HO795511 | 484 | 341 | 811 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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