y
Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si022143m |
Family | GT47 |
Protein Properties | Length: 424 Molecular Weight: 46867.8 Isoelectric Point: 7.0411 |
Chromosome | Chromosome/Scaffold: 3 Start: 17641510 End: 17645022 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 53 | 351 | 0 |
RLKVYVYDLPAKYNTKLVEDDPRCLTHMFATEVFVHRSLLSSAVRTLDPEEADWFYAPVYTTCDLTASGHPMPFDSPRMMRAAIRLISRRWPYWNRTEGA DHFFVTPHDFGACFHFKEAKAVARGILPVLRRATLVQTFGQSGHACMKEEGGGSITVPPYAPPGRMEARLLPPGTPRSVFAYFRGLFYDAGNDPGGGYYA RGARAAVWENFRSSPLFDISAERPATYYEDMQRAVFCLCPLGWAPWSPRLVEAVVFGCIPVVIADGIVLPFADAIPWAEIGVFVAEEDVPRLDTILTSI |
Full Sequence |
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Protein Sequence Length: 424 Download |
MKMRSVLAIA ILATTTAAVL FLGSEAQEVK KDHRTYRISG SAGDVLEDDP VGRLKVYVYD 60 LPAKYNTKLV EDDPRCLTHM FATEVFVHRS LLSSAVRTLD PEEADWFYAP VYTTCDLTAS 120 GHPMPFDSPR MMRAAIRLIS RRWPYWNRTE GADHFFVTPH DFGACFHFKE AKAVARGILP 180 VLRRATLVQT FGQSGHACMK EEGGGSITVP PYAPPGRMEA RLLPPGTPRS VFAYFRGLFY 240 DAGNDPGGGY YARGARAAVW ENFRSSPLFD ISAERPATYY EDMQRAVFCL CPLGWAPWSP 300 RLVEAVVFGC IPVVIADGIV LPFADAIPWA EIGVFVAEED VPRLDTILTS IPPEEVLRKQ 360 RFLASPAVKR AVQFPQPSQP GDAFHQILNG LARKLPHGEG VFLSPGQTVL NWTDGPPGDL 420 KPW* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-74 | 53 | 351 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACG31432.1 | 0 | 12 | 423 | 11 | 419 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
RefSeq | NP_001045264.1 | 0 | 27 | 423 | 24 | 417 | Os01g0926700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001149319.1 | 0 | 25 | 423 | 26 | 421 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
RefSeq | XP_002284685.1 | 0 | 4 | 423 | 5 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002441217.1 | 0 | 1 | 423 | 1 | 422 | hypothetical protein SORBIDRAFT_09g022500 [Sorghum bicolor] |