Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si024048m |
Family | GH19 |
Protein Properties | Length: 281 Molecular Weight: 29386 Isoelectric Point: 6.9334 |
Chromosome | Chromosome/Scaffold: 3 Start: 21490621 End: 21491730 |
Description | basic chitinase |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH19 | 65 | 133 | 8.4e-28 |
VASVVPRDLFERLLLHRNDAACPARGFYTYDAFIAAAAAFPGFGTTGSDEQRKREVAAFLGQTSHGTTG | |||
GH19 | 143 | 263 | 0 |
FSWGYNYNYGPAGRVIGVDLLNNPDLEATDAVVSFKMALWFWMTPRDNKPSCHAVITGQWTPTDADRAAGRGAPGYGVITNIINGGLECGRGPDLRVADR IGFYKRYCHAFRIGYGSDLDC |
Full Sequence |
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Protein Sequence Length: 281 Download |
MSTSSGAPSP AAIATAVPQC GSQAGGKLCH NCLCCSRFGF CGDTDPYCGA GCVTPPGPRP 60 VPGDVASVVP RDLFERLLLH RNDAACPARG FYTYDAFIAA AAAFPGFGTT GSDEQRKREV 120 AAFLGQTSHG TTGGWATAPD GPFSWGYNYN YGPAGRVIGV DLLNNPDLEA TDAVVSFKMA 180 LWFWMTPRDN KPSCHAVITG QWTPTDADRA AGRGAPGYGV ITNIINGGLE CGRGPDLRVA 240 DRIGFYKRYC HAFRIGYGSD LDCDGQRPFN AAVAAGLAAQ * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd06921 | ChtBD1_GH19_hevein | 2.0e-10 | 19 | 52 | 34 | + Hevein or Type 1 chitin binding domain subfamily co-occuring with family 19 glycosyl hydrolases or with barwin domains. This subfamily includes Hevein, a major IgE-binding allergen in natural rubber latex. ChtBD1 is a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements. | ||
smart00270 | ChtBD1 | 1.0e-10 | 19 | 55 | 37 | + Chitin binding domain. | ||
pfam00187 | Chitin_bind_1 | 4.0e-12 | 19 | 55 | 37 | + Chitin recognition protein. | ||
cd00325 | chitinase_glyco_hydro_19 | 2.0e-94 | 69 | 263 | 231 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
pfam00182 | Glyco_hydro_19 | 3.0e-98 | 68 | 263 | 233 | + Chitinase class I. |
Gene Ontology | |
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GO Term | Description |
GO:0004568 | chitinase activity |
GO:0006032 | chitin catabolic process |
GO:0008061 | chitin binding |
GO:0016998 | cell wall macromolecule catabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAF04454.1 | 0 | 12 | 269 | 15 | 318 | AF000966_1 chitinase [Poa pratensis] |
GenBank | ACJ23248.1 | 0 | 19 | 269 | 23 | 315 | class I chitinase [Festuca arundinacea] |
RefSeq | NP_001150560.1 | 0 | 29 | 280 | 43 | 334 | LOC100284192 [Zea mays] |
Swiss-Prot | Q9FRV1 | 0 | 12 | 269 | 13 | 320 | CHIA_SECCE RecName: Full=Basic endochitinase A; AltName: Full=Rye seed chitinase-a; Short=RSC-a; Flags: Precursor |
RefSeq | XP_002441062.1 | 0 | 18 | 280 | 78 | 379 | hypothetical protein SORBIDRAFT_09g019660 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3iwr_B | 0 | 17 | 280 | 1 | 309 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 3iwr_A | 0 | 17 | 280 | 1 | 309 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 2dkv_A | 0 | 17 | 280 | 1 | 309 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
PDB | 4dyg_B | 0 | 65 | 269 | 3 | 243 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
PDB | 4dyg_A | 0 | 65 | 269 | 3 | 243 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777873 | 289 | 19 | 269 | 0 |
BU103710 | 308 | 19 | 270 | 0 |
FF349469 | 287 | 12 | 249 | 0 |
FE679584 | 288 | 19 | 269 | 0 |
ES903004 | 291 | 15 | 262 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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