| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si024608m |
| Family | GT47 |
| Protein Properties | Length: 530 Molecular Weight: 58755.4 Isoelectric Point: 5.5021 |
| Chromosome | Chromosome/Scaffold: 3 Start: 6248457 End: 6250134 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 92 | 418 | 0 |
| SCEGRYVYMLDVPSRFDMLRDCVPGSPLFDDMWSWCAITVNAGLGPKIAGNGSDGDTDIIPSTGWYSTDQYALEVMFHNWMRRYECLTGDPSAATAVYVP YYPALELHQHLCGYNTTARDGPSEAFLRWLSSQPTWAALGGRDHFMVAAKTTWMFRREPGGGDGGCGNNFLGQPESGNMTVLTYESNIWAPRDIAVPYPS YFHPTSAGEVAAWQARARAAPRPFLFAFAGARRIKGQLAIRDRVFDVCESAAARGRCGLVDCSHGLEGSITCRTAAKLVALFASARFCLQPRGDSFMRRS SIDSVMAGCIPVFFHRASTLEAQYRWH | |||
| Full Sequence |
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| Protein Sequence Length: 530 Download |
| MEAHYPKYLL YCLLIAGSWL LSCLLHFQYL HVALSSSSFA APRRAALVVL PAALDASFLP 60 APAVEADDKR WSTSSVVASS PSPSSSPPPP PSCEGRYVYM LDVPSRFDML RDCVPGSPLF 120 DDMWSWCAIT VNAGLGPKIA GNGSDGDTDI IPSTGWYSTD QYALEVMFHN WMRRYECLTG 180 DPSAATAVYV PYYPALELHQ HLCGYNTTAR DGPSEAFLRW LSSQPTWAAL GGRDHFMVAA 240 KTTWMFRREP GGGDGGCGNN FLGQPESGNM TVLTYESNIW APRDIAVPYP SYFHPTSAGE 300 VAAWQARARA APRPFLFAFA GARRIKGQLA IRDRVFDVCE SAAARGRCGL VDCSHGLEGS 360 ITCRTAAKLV ALFASARFCL QPRGDSFMRR SSIDSVMAGC IPVFFHRAST LEAQYRWHEP 420 EPGRDGDGGR RRYYVLLNAD DVLEGRVDIE EELSRYSDEE VAEMREEVIR MIPRFLYRDT 480 RVRFEGEMRD AFDITMDGVM DRMRRIKNGE NVVLKGYDDS DEAMAASDS* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 8.0e-35 | 93 | 405 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABA96790.1 | 0 | 1 | 529 | 1 | 527 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
| DDBJ | BAH95576.1 | 0 | 157 | 529 | 94 | 466 | Os12g0224400 [Oryza sativa Japonica Group] |
| GenBank | EEC69035.1 | 0 | 109 | 529 | 1 | 391 | hypothetical protein OsI_37846 [Oryza sativa Indica Group] |
| GenBank | EEE52961.1 | 0 | 109 | 529 | 1 | 424 | hypothetical protein OsJ_35605 [Oryza sativa Japonica Group] |
| RefSeq | XP_002443053.1 | 0 | 1 | 522 | 1 | 519 | hypothetical protein SORBIDRAFT_08g007160 [Sorghum bicolor] |
