Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si025042m |
Family | GT47 |
Protein Properties | Length: 578 Molecular Weight: 63727.6 Isoelectric Point: 9.7311 |
Chromosome | Chromosome/Scaffold: 3 Start: 41058914 End: 41060647 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 164 | 506 | 0 |
CAGRYIYVQELPSRFNADLLRNCRSLSEWTDMCRHVANAGMGPRLTRTGAVLPATGWYDTNQFTLEVIFHGRMRQYGCLTADASRADAVYVPYYAGLDVG RHLWGSSNGARDALAEDLAGWLRSTPAWAARGGRDHFLVGGRIAWDFRRQDGGNWGSRLLLLPEAANMTALVLESGPWHAGDVAVPYPTCFHPSRTAEVA SCQRALRRARRPWLFAFAGARRPGGAGGGGTLRDAVIGQCARSRRCGLLQCGRGRRHDCYAPGNVVRHFKSAAFCLQPPGDSYTRRSAFDAMLAGCVPVF FHPGSAYTQYRWHLPADHARYSVFVPGDGVRNGTVRVEDVLRR |
Full Sequence |
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Protein Sequence Length: 578 Download |
MGSGRASAVL RAARWLLPLV VPACCVVWTI LFFAPPTPPA LDVGRRESFH VSVGEIVGAT 60 ARRAAVTMPV PEREGIVHAS PRLPERQEII DTLPPPPPER RARAETSPPP PPLPPPEHEL 120 IVDASPPPPP KLEEITGTSP PPPQLARQGR QGRAANRAAA ADRCAGRYIY VQELPSRFNA 180 DLLRNCRSLS EWTDMCRHVA NAGMGPRLTR TGAVLPATGW YDTNQFTLEV IFHGRMRQYG 240 CLTADASRAD AVYVPYYAGL DVGRHLWGSS NGARDALAED LAGWLRSTPA WAARGGRDHF 300 LVGGRIAWDF RRQDGGNWGS RLLLLPEAAN MTALVLESGP WHAGDVAVPY PTCFHPSRTA 360 EVASCQRALR RARRPWLFAF AGARRPGGAG GGGTLRDAVI GQCARSRRCG LLQCGRGRRH 420 DCYAPGNVVR HFKSAAFCLQ PPGDSYTRRS AFDAMLAGCV PVFFHPGSAY TQYRWHLPAD 480 HARYSVFVPG DGVRNGTVRV EDVLRRFSRA EVAAMREQVI RMIPSIVYRD PRVPGDGFRD 540 AFDIAVDGMI ERVSRIKRGL PPWEEDRDQR RWDGYFDS |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-45 | 168 | 507 | 352 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA99677.1 | 0 | 164 | 578 | 97 | 525 | Exostosin family protein, expressed [Oryza sativa (japonica cultivar-group)] |
GenBank | EAY83600.1 | 0 | 164 | 578 | 97 | 525 | hypothetical protein OsI_38822 [Oryza sativa Indica Group] |
RefSeq | XP_002442366.1 | 0 | 1 | 578 | 1 | 585 | hypothetical protein SORBIDRAFT_08g018880 [Sorghum bicolor] |