Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si025194m |
Family | GT47 |
Protein Properties | Length: 454 Molecular Weight: 51694.5 Isoelectric Point: 8.8289 |
Chromosome | Chromosome/Scaffold: 3 Start: 2005851 End: 2008579 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 42 | 381 | 0 |
PLRVYVADLPRELNYGLLDRYWSLPATDSRIPASSDPDHPAPRNHPPYPESPLIKQYSAEYWLLASLRTAAMAAVRVVADWREADVVFVPFFATLSAEME LGWGTKGAFRKEDGNEDYRRQREVVDRVTAHPAWRRSGGRDHIFVLTDPVAMWHVRTEIAPAILLVVDFGGWYKLDSKTASRNSSHMIQHTQVSLLKDVI VPYTHLLPTLPLSENKDRPTLLYFKGAKHRHRGGLVREKLWDLLGNEPDIVMEEGFPNATGREQSIKGMRASEFCLHPAGDTPTSCRLFDAIASLCIPVI VSDEVELPFEGMVDYTEFSIFVSVSNAMRPKWLTNYLRNI |
Full Sequence |
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Protein Sequence Length: 454 Download |
MKRLAVLAVS VLLLLLPLSF FLLRPTSPPL LPSRQVFEPD RPLRVYVADL PRELNYGLLD 60 RYWSLPATDS RIPASSDPDH PAPRNHPPYP ESPLIKQYSA EYWLLASLRT AAMAAVRVVA 120 DWREADVVFV PFFATLSAEM ELGWGTKGAF RKEDGNEDYR RQREVVDRVT AHPAWRRSGG 180 RDHIFVLTDP VAMWHVRTEI APAILLVVDF GGWYKLDSKT ASRNSSHMIQ HTQVSLLKDV 240 IVPYTHLLPT LPLSENKDRP TLLYFKGAKH RHRGGLVREK LWDLLGNEPD IVMEEGFPNA 300 TGREQSIKGM RASEFCLHPA GDTPTSCRLF DAIASLCIPV IVSDEVELPF EGMVDYTEFS 360 IFVSVSNAMR PKWLTNYLRN ISKQQKDEFR RNLAHVQPIF EYDTSYSSSR TPDGAVNYIW 420 KKIHQKLPTI QEAIIREKRK PYGALIPLRC HCT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-67 | 39 | 381 | 355 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAE02830.1 | 0 | 24 | 453 | 23 | 464 | OSJNBa0043A12.35 [Oryza sativa (japonica cultivar-group)] |
GenBank | EEC78225.1 | 0 | 24 | 453 | 23 | 452 | hypothetical protein OsI_17865 [Oryza sativa Indica Group] |
RefSeq | NP_001137073.1 | 0 | 24 | 453 | 24 | 458 | hypothetical protein LOC100217246 [Zea mays] |
RefSeq | XP_002448739.1 | 0 | 24 | 453 | 24 | 456 | hypothetical protein SORBIDRAFT_06g032380 [Sorghum bicolor] |
RefSeq | XP_002533317.1 | 0 | 43 | 453 | 55 | 478 | catalytic, putative [Ricinus communis] |