| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si026308m |
| Family | GT47 |
| Protein Properties | Length: 478 Molecular Weight: 52687.9 Isoelectric Point: 9.6616 |
| Chromosome | Chromosome/Scaffold: 8 Start: 431032 End: 434100 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 102 | 414 | 0 |
| AVRVFMYDMPPEFHFGLLGWSPPSPDSVWPDLSTPPPRYPGGLNQQHSVEYWLTLDLLSSSSAPCGPAVRVADSRDADLVFVPFFASLSYNRHSRPVPPE KVARDKALQEKLVRYLSARPEWKRYGGADHVIVAHHPNSLLHARGPLSPAVFVLSDFGRYHPRVASLEKDVIAPYKHMAKTFVNDSAGFDNRPTLLYFRG AIYRKEGGSIRQELYYMLKDEKNVYFSFGSVQDHGASKASQGMHSSKFCLNIAGDTPSSNRLFDAIVSHCVPVIISDDIELPYEDVLNYSKFSIFVRSSD AVKKGYLMRLISG | |||
| Full Sequence |
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| Protein Sequence Length: 478 Download |
| MAPRGRTLLL PLAAATVLVA STIFLFAAAA GVRWRPADTG LPVPPHAFSA AAVPVTATAS 60 SNTTPGARKE LSFLDENGHP DDPGSSSGSD AGAAGCDPRG AAVRVFMYDM PPEFHFGLLG 120 WSPPSPDSVW PDLSTPPPRY PGGLNQQHSV EYWLTLDLLS SSSAPCGPAV RVADSRDADL 180 VFVPFFASLS YNRHSRPVPP EKVARDKALQ EKLVRYLSAR PEWKRYGGAD HVIVAHHPNS 240 LLHARGPLSP AVFVLSDFGR YHPRVASLEK DVIAPYKHMA KTFVNDSAGF DNRPTLLYFR 300 GAIYRKEGGS IRQELYYMLK DEKNVYFSFG SVQDHGASKA SQGMHSSKFC LNIAGDTPSS 360 NRLFDAIVSH CVPVIISDDI ELPYEDVLNY SKFSIFVRSS DAVKKGYLMR LISGVSKQQW 420 TRMWNRLKEV DKHFEYQYPS QKDDAVQMIW QALARRVPAI QLKVHRSSRF SRSGRGK* 480 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-57 | 99 | 404 | 316 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABA91286.2 | 0 | 31 | 476 | 30 | 474 | secondary cell wall-related glycosyltransferase family 47, putative, expressed [Oryza sativa (japonica cultivar-group)] |
| GenBank | EEC67582.1 | 0 | 31 | 476 | 30 | 481 | hypothetical protein OsI_34941 [Oryza sativa Indica Group] |
| GenBank | EEE52679.1 | 0 | 44 | 477 | 96 | 528 | hypothetical protein OsJ_35064 [Oryza sativa Japonica Group] |
| RefSeq | NP_001066040.1 | 0 | 31 | 477 | 30 | 475 | Os12g0124400 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001151894.1 | 0 | 1 | 477 | 1 | 488 | secondary cell wall-related glycosyltransferase family 47 [Zea mays] |
