| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si028815m |
| Family | GH31 |
| Protein Properties | Length: 986 Molecular Weight: 108328 Isoelectric Point: 5.1346 |
| Chromosome | Chromosome/Scaffold: 2 Start: 11419370 End: 11430719 |
| Description | heteroglycan glucosidase 1 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH31 | 170 | 580 | 0 |
| KTPADVMTSLSHAIGTVSMPPKWSLGYHQCRWSYDSSEKVLKVIRTFREKGIPCDVVWMDIDYMDGFRCFTFDSKRFPDPKAMVDDLHSIGCQAIWMLDP GIKKEEDYFVYDSGTKNDVWIQKADGSPFVGEVWPGDCVFPDYTSEKTRAWWAGLVKDFISNGVDGIWNDMNEPAVFNTTTKTMPESNIHRGDADIGGVK NHSYYHNVYGMLMARSTYEGMAMGNAAKRPFVLTRAGFIGSQRYAATWTGDNLSNWEHLHMSLPMVLQLGLSGQPLSGPDIGGFAGNATPKLFGRWMGVG ALFPFSRGHTETGSIDHEPWSFGEECEEVCRLALLRRYRLLPHIYTLFYHSHTKGIPVATPVFFADPQDPELRKVETSFLLGPLLVCASTLPNKGAHECA HTLPKGIWLPF | |||
| Full Sequence |
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| Protein Sequence Length: 986 Download |
| MAAAAAAAGE MVWMRVLEEG VFRFDASEAA RAAAGPSLSF ADPRWREAAR EGADAPAVVP 60 ACEAAPGGAQ KVVLKLPSGT SLYGTGEASG PLERTGKRVF TWNTDAWGFG SGTTSLYQSH 120 PWVLAVLPDG KALGVLADTT RRCEIDLREE STIKFSASSA YPVITFGPFK TPADVMTSLS 180 HAIGTVSMPP KWSLGYHQCR WSYDSSEKVL KVIRTFREKG IPCDVVWMDI DYMDGFRCFT 240 FDSKRFPDPK AMVDDLHSIG CQAIWMLDPG IKKEEDYFVY DSGTKNDVWI QKADGSPFVG 300 EVWPGDCVFP DYTSEKTRAW WAGLVKDFIS NGVDGIWNDM NEPAVFNTTT KTMPESNIHR 360 GDADIGGVKN HSYYHNVYGM LMARSTYEGM AMGNAAKRPF VLTRAGFIGS QRYAATWTGD 420 NLSNWEHLHM SLPMVLQLGL SGQPLSGPDI GGFAGNATPK LFGRWMGVGA LFPFSRGHTE 480 TGSIDHEPWS FGEECEEVCR LALLRRYRLL PHIYTLFYHS HTKGIPVATP VFFADPQDPE 540 LRKVETSFLL GPLLVCASTL PNKGAHECAH TLPKGIWLPF DFADSHPDLP VLYLRGGAIL 600 PVGPPIKHVG EASLEDDLSL IIALDENGKA EGVLFEDAGD GYKFTQGDYL LTYYTAELHS 660 SVVTVKVFKS EGSWKRPKRN LKINILLGGG AMISADGVDG GEIHLTMPPE SEVSSLVATS 720 ELECKKRLEM IQPIPDTDEP SRQEGAELSK IPVDLKSGDW LLKVVPGIGG RIISMTHLPS 780 DSQWLHSRIE INGYEEYSGT EYRSAGCTEE YNVIRRYLEQ SGEEESICME GDIGGGLVLQ 840 RQISILKDNP KIVQIESSIQ ARSVGAGSGG FSRLVCLRVH PTFTLLHPTE VVVAFTAVNG 900 SKQEISPESG EITFEGDLRP NGEWMLVDKC VGLSLVNRFD PSEVSKCMVH WGTGDVNMEL 960 WSEERPVSKD TPLRICHQYE VRQTN* 1020 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06603 | GH31_GANC_GANAB_alpha | 3.0e-127 | 184 | 524 | 345 | + This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae. | ||
| COG1501 | COG1501 | 4.0e-137 | 74 | 700 | 652 | + Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism] | ||
| pfam01055 | Glyco_hydro_31 | 3.0e-161 | 164 | 600 | 455 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. | ||
| PLN02763 | PLN02763 | 0 | 9 | 984 | 976 | + hydrolase, hydrolyzing O-glycosyl compounds | ||
| cd06604 | GH31_glucosidase_II_MalA | 0 | 184 | 524 | 342 | + Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized in Bacillus thermoamyloliquefaciens where it forms a homohexamer. This family also includes the MalA alpha-glucosidase from Sulfolobus sulfataricus and the AglA alpha-glucosidase from Picrophilus torridus. MalA is part of the carbohydrate-metabolizing machinery that allows this organism to utilize carbohydrates, such as maltose, as the sole carbon and energy source. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAG72144.1 | 0 | 5 | 984 | 2 | 979 | alpha-glucosidase like protein [Hordeum vulgare subsp. vulgare] |
| GenBank | EEC81922.1 | 0 | 11 | 985 | 1 | 974 | hypothetical protein OsI_25772 [Oryza sativa Indica Group] |
| GenBank | EEE67050.1 | 0 | 11 | 985 | 1 | 973 | hypothetical protein OsJ_23995 [Oryza sativa Japonica Group] |
| RefSeq | NP_001059480.1 | 0 | 2 | 985 | 76 | 1080 | Os07g0420700 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001059483.1 | 0 | 4 | 985 | 2 | 980 | Os07g0421300 [Oryza sativa (japonica cultivar-group)] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2g3n_F | 0 | 84 | 615 | 66 | 624 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| PDB | 2g3n_E | 0 | 84 | 615 | 66 | 624 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| PDB | 2g3n_D | 0 | 84 | 615 | 66 | 624 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| PDB | 2g3n_C | 0 | 84 | 615 | 66 | 624 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| PDB | 2g3n_B | 0 | 84 | 615 | 66 | 624 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| starch degradation I | RXN-2141 | EC-3.2.1.20 | α-glucosidase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO779383 | 644 | 339 | 981 | 0 |
| GT034560 | 340 | 644 | 983 | 0 |
| GT034868 | 338 | 644 | 981 | 0 |
| GO882018 | 324 | 339 | 662 | 0 |
| EB672844 | 271 | 675 | 945 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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