Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si029318m |
Family | AA3 |
Protein Properties | Length: 583 Molecular Weight: 63537.5 Isoelectric Point: 8.8533 |
Chromosome | Chromosome/Scaffold: 2 Start: 28187486 End: 28192203 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 45 | 575 | 0 |
PTTYDYIVVGGGTAGCPLAATLSLKYRVLLLERGGSPYGNRNVSYMENFHIGLMNMAPDSSSQAFISTDGVINARARVLGGGTCINAGFYSRASSSFIQE VGWDEDLVNKSFPWVEEKIVQWPKIAPWQAALRDGLLQAGVAPFNGYTYDHVSGTKVGGTIFDETGYRHTAADLLAAGDPNNLRVLLHASVHKIVFDSRQ GRLKPRAIGVQFTDENGRHHQAFLNNNKNSEIIVSAGAIGTPQLLLLSGIGPKNHLKSHNIPVVLHNKYVGKGMADNPMNSIFIPTRSPPRQSLIETVGI TEEGVFIEASSGFGQSSESVHCHHGIMSAEIGQLSTIPPKQRTLEAAQKYAHNKLNLPKEVFHGGFILEKIDGPLSTGHLVLTDTDVRNNPAVTFNYFSH PQDLDRCVYGIKTIERILKTNRFSELAADGTGFSMERVLNMSVQANVNLIPKHTNDTESLGQFCKDTVITIWHYHGGCHVGKVVDQHYRVLGVSGIRVVD GSTFSKSPGTNPQATVMMMGRYMGVKILRER |
Full Sequence |
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Protein Sequence Length: 583 Download |
MAFSVFIKLL ACLLCFFELS QGKQQFTLNN LPPLRKASSY PTGCPTTYDY IVVGGGTAGC 60 PLAATLSLKY RVLLLERGGS PYGNRNVSYM ENFHIGLMNM APDSSSQAFI STDGVINARA 120 RVLGGGTCIN AGFYSRASSS FIQEVGWDED LVNKSFPWVE EKIVQWPKIA PWQAALRDGL 180 LQAGVAPFNG YTYDHVSGTK VGGTIFDETG YRHTAADLLA AGDPNNLRVL LHASVHKIVF 240 DSRQGRLKPR AIGVQFTDEN GRHHQAFLNN NKNSEIIVSA GAIGTPQLLL LSGIGPKNHL 300 KSHNIPVVLH NKYVGKGMAD NPMNSIFIPT RSPPRQSLIE TVGITEEGVF IEASSGFGQS 360 SESVHCHHGI MSAEIGQLST IPPKQRTLEA AQKYAHNKLN LPKEVFHGGF ILEKIDGPLS 420 TGHLVLTDTD VRNNPAVTFN YFSHPQDLDR CVYGIKTIER ILKTNRFSEL AADGTGFSME 480 RVLNMSVQAN VNLIPKHTND TESLGQFCKD TVITIWHYHG GCHVGKVVDQ HYRVLGVSGI 540 RVVDGSTFSK SPGTNPQATV MMMGRYMGVK ILRERLGRAA GV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam05199 | GMC_oxred_C | 8.0e-28 | 418 | 564 | 152 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR03970 | Rv0697 | 5.0e-29 | 49 | 564 | 562 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
TIGR01810 | betA | 3.0e-35 | 49 | 564 | 576 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 5.0e-50 | 47 | 580 | 591 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 1 | 582 | 590 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACF81814.1 | 0 | 20 | 582 | 28 | 591 | unknown [Zea mays] |
GenBank | ACG29139.1 | 0 | 20 | 582 | 27 | 590 | protein HOTHEAD precursor [Zea mays] |
GenBank | EAZ08804.1 | 0 | 1 | 582 | 1 | 585 | hypothetical protein OsI_31066 [Oryza sativa Indica Group] |
RefSeq | NP_001130910.1 | 0 | 20 | 582 | 28 | 591 | hypothetical protein LOC100192014 [Zea mays] |
RefSeq | XP_002462276.1 | 0 | 20 | 582 | 26 | 591 | hypothetical protein SORBIDRAFT_02g023010 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3red_L | 0 | 47 | 575 | 26 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_K | 0 | 47 | 575 | 26 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_J | 0 | 47 | 575 | 26 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_I | 0 | 47 | 575 | 26 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_H | 0 | 47 | 575 | 26 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |