| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si030423m |
| Family | CE10 |
| Protein Properties | Length: 339 Molecular Weight: 36358.9 Isoelectric Point: 5.2371 |
| Chromosome | Chromosome/Scaffold: 2 Start: 3378038 End: 3379382 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 40 | 332 | 0 |
| ATPVRDDGSVEWKDATFDEAAGLGLRLYRPRERGGRSRLPVFFYYHGGGFCIGSRAWPNCQNYCLRLAADLGALVVAPDYRLAPEHRLPAAIDDGAAAVL WLAAQGRTPGGGGDPWVAESADLGRVFVSGDSAGGTIAHHLAVRFGSPDGRAELAPAAVAIRGYVQLMPFFGGVQRTRSEAECPDDAFLNRPLNDRYWRL SLPEGATADHPVANPFGPGAPPLEGVELAPTLVVVGGRDILHDRAVDYAARLRAMGKPVEVRDFEGQQHGFFTIDPWSDASAELMRVIKRFVD | |||
| Full Sequence |
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| Protein Sequence Length: 339 Download |
| MASEAAASAE PAPQVVDECR GVLFVYSDGT VVRRAQPGFA TPVRDDGSVE WKDATFDEAA 60 GLGLRLYRPR ERGGRSRLPV FFYYHGGGFC IGSRAWPNCQ NYCLRLAADL GALVVAPDYR 120 LAPEHRLPAA IDDGAAAVLW LAAQGRTPGG GGDPWVAESA DLGRVFVSGD SAGGTIAHHL 180 AVRFGSPDGR AELAPAAVAI RGYVQLMPFF GGVQRTRSEA ECPDDAFLNR PLNDRYWRLS 240 LPEGATADHP VANPFGPGAP PLEGVELAPT LVVVGGRDIL HDRAVDYAAR LRAMGKPVEV 300 RDFEGQQHGF FTIDPWSDAS AELMRVIKRF VDSDGRFD* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam00135 | COesterase | 4.0e-7 | 67 | 190 | 139 | + Carboxylesterase family. |
| cd00312 | Esterase_lipase | 3.0e-7 | 47 | 224 | 192 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. |
| PRK10162 | PRK10162 | 3.0e-10 | 65 | 310 | 254 | + acetyl esterase; Provisional |
| COG0657 | Aes | 1.0e-38 | 39 | 333 | 296 | + Esterase/lipase [Lipid metabolism] |
| pfam07859 | Abhydrolase_3 | 1.0e-69 | 81 | 311 | 231 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI24401.1 | 0 | 12 | 331 | 20 | 329 | unnamed protein product [Vitis vinifera] |
| GenBank | EAZ02867.1 | 0 | 15 | 335 | 7 | 322 | hypothetical protein OsI_24998 [Oryza sativa Indica Group] |
| RefSeq | NP_001058951.1 | 0 | 15 | 335 | 7 | 322 | Os07g0162900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002277507.1 | 0 | 12 | 331 | 3 | 312 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002461501.1 | 0 | 8 | 338 | 2 | 327 | hypothetical protein SORBIDRAFT_02g003630 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ed1_F | 4.06377e-44 | 29 | 334 | 45 | 350 | A Chain A, Structure Of Alpha-Galactosidase From Lactobacillus Acidophilus Ncfm With Galactose |
| PDB | 3ed1_E | 4.06377e-44 | 29 | 334 | 45 | 350 | A Chain A, Structure Of Alpha-Galactosidase From Lactobacillus Acidophilus Ncfm With Galactose |
| PDB | 3ed1_D | 4.06377e-44 | 29 | 334 | 45 | 350 | A Chain A, Structure Of Alpha-Galactosidase From Lactobacillus Acidophilus Ncfm With Galactose |
| PDB | 3ed1_C | 4.06377e-44 | 29 | 334 | 45 | 350 | A Chain A, Structure Of Alpha-Galactosidase From Lactobacillus Acidophilus Ncfm With Galactose |
| PDB | 3ed1_B | 4.06377e-44 | 29 | 334 | 45 | 350 | A Chain A, Structure Of Alpha-Galactosidase From Lactobacillus Acidophilus Ncfm With Galactose |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| FL908143 | 241 | 75 | 315 | 0 |
| EE046334 | 263 | 15 | 274 | 0 |
| EC894209 | 261 | 15 | 272 | 0 |
| FL950122 | 237 | 14 | 250 | 0 |
| EE046335 | 241 | 15 | 252 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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