y
Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si034324m |
Family | GT47 |
Protein Properties | Length: 784 Molecular Weight: 88763.8 Isoelectric Point: 7.117 |
Chromosome | Chromosome/Scaffold: 9 Start: 55001601 End: 55006355 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 337 | 691 | 0 |
KKRPLIYVYDLPAEFDNHLLEGRHFKFQCVNRIYDGRNRTLWTQQLYGAQMALYESILASPHRTLNGDEADYFYVPVLDSCLITRSDDAPHLLMPRDLRL RSYHALEYYRMAYDHIAQQYPYWNRTSGRDHIWFFSWDEGACYAPREIWNSMMLVHWGNTNTKHKNSTSAYWADNWDHIPLDRRGNHPCFDPRKDLVLPA WKEPDPGAIWLKLWARPRINRTTLFYFNGNLGPAYEGGRPEDTYSMGIRQKLAAEFGSTPNKQGNLGRQYATDVTVTYLRTEKYYEELASSVFCGVLPGD GWSGRMEDSMLQGCIPVIIQDGIFLPYENVLNYNSFAVRLQEDDIPNLISTLRGI |
Full Sequence |
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Protein Sequence Length: 784 Download |
MLAIRSTKCP VAFVGAAGAL VVLVTAVHVF MVPILPSSLD YFGARSSISR PRNALPGVGV 60 VDSRLRGQFP SDSHGAVVFR GAPWKAEVGR WLAGCHANSS SVNVTEAIGA KRCEKDCSGR 120 GVCNYNLGEC RCFHGYSGKG CEEVLKLECN LPSSPEWPAG RWIVSICAAH CDTTRAMCFC 180 GPGTKYPDRP VAEACGFKTI FPAKPDDPKL TDWKTPDLEN VFTTNRSKLG WCNVVPEDAY 240 SSKVKYKEEC DCKYDGLWGQ FCETRVECSC INQCSGHGHC RGGFCQCDSG YFGIDCSIPS 300 AHSLAHDLPS WLHPPVNLPD LKIVNSTSIN VKAIVQKKRP LIYVYDLPAE FDNHLLEGRH 360 FKFQCVNRIY DGRNRTLWTQ QLYGAQMALY ESILASPHRT LNGDEADYFY VPVLDSCLIT 420 RSDDAPHLLM PRDLRLRSYH ALEYYRMAYD HIAQQYPYWN RTSGRDHIWF FSWDEGACYA 480 PREIWNSMML VHWGNTNTKH KNSTSAYWAD NWDHIPLDRR GNHPCFDPRK DLVLPAWKEP 540 DPGAIWLKLW ARPRINRTTL FYFNGNLGPA YEGGRPEDTY SMGIRQKLAA EFGSTPNKQG 600 NLGRQYATDV TVTYLRTEKY YEELASSVFC GVLPGDGWSG RMEDSMLQGC IPVIIQDGIF 660 LPYENVLNYN SFAVRLQEDD IPNLISTLRG INETQVEFML GNVRQMWQRF FYRDSILLEA 720 QRQKRLFSEE APWSVEVSKL PDDDDVFATF MQVLHYKLYN DPWRQGLLQT KETGLPTICS 780 RAS* 840 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00054 | EGF_CA | 0.003 | 267 | 296 | 34 | + Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. | ||
pfam07974 | EGF_2 | 6.0e-5 | 268 | 296 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
pfam03016 | Exostosin | 2.0e-70 | 336 | 691 | 357 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0005515 | protein binding |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI29877.1 | 0 | 4 | 779 | 33 | 817 | unnamed protein product [Vitis vinifera] |
GenBank | EAZ25771.1 | 0 | 4 | 783 | 1 | 779 | hypothetical protein OsJ_09611 [Oryza sativa Japonica Group] |
GenBank | EEC74609.1 | 0 | 4 | 783 | 1 | 737 | hypothetical protein OsI_10218 [Oryza sativa Indica Group] |
RefSeq | NP_191322.3 | 0 | 1 | 779 | 1 | 788 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002277596.1 | 0 | 4 | 779 | 5 | 789 | PREDICTED: hypothetical protein [Vitis vinifera] |