Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si036186m |
Family | GT57 |
Protein Properties | Length: 379 Molecular Weight: 42298.8 Isoelectric Point: 9.5353 |
Chromosome | Chromosome/Scaffold: 9 Start: 47327192 End: 47329165 |
Description | ALG6, ALG8 glycosyltransferase family |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT57 | 41 | 373 | 0 |
LLVRVLVSMGPYSGQGAAPKFGDYEAQRHWMELTLHLPPSDWYRNTSDNDLAYWGLDYPPLSAYQSLLHGRIINASLPDAVALRSSRGYESPESKLLMRW TVLSSDLLVFFPAALWFVWAYIKGGIGTSGEEKREGWLWLLAMVLISPCLVLIDHGHFQYNCISLGLTLGAIAGVLSRNELIAAALFTLAINHKQMSLYF APAFFSHLLGKCLKRKYPIVEVMKLAFVVLGTFALVWWPFLRSFEAALQVISRLAPFERGIYEDYVANFWCSTSVIIKWKILFAIKPLKLMSLSATVLAF LPSFVQQVKSPSNLGFLYSLMNSSFSFYLFSYQ |
Full Sequence |
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Protein Sequence Length: 379 Download |
MAKPKKPRAS APDPPAAAAR LPWHPPAPPV PTALLISLAA LLVRVLVSMG PYSGQGAAPK 60 FGDYEAQRHW MELTLHLPPS DWYRNTSDND LAYWGLDYPP LSAYQSLLHG RIINASLPDA 120 VALRSSRGYE SPESKLLMRW TVLSSDLLVF FPAALWFVWA YIKGGIGTSG EEKREGWLWL 180 LAMVLISPCL VLIDHGHFQY NCISLGLTLG AIAGVLSRNE LIAAALFTLA INHKQMSLYF 240 APAFFSHLLG KCLKRKYPIV EVMKLAFVVL GTFALVWWPF LRSFEAALQV ISRLAPFERG 300 IYEDYVANFW CSTSVIIKWK ILFAIKPLKL MSLSATVLAF LPSFVQQVKS PSNLGFLYSL 360 MNSSFSFYLF SYQGMFYC* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03155 | Alg6_Alg8 | 4.0e-98 | 48 | 373 | 331 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. |
Gene Ontology | |
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GO Term | Description |
GO:0005789 | endoplasmic reticulum membrane |
GO:0016758 | transferase activity, transferring hexosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACR38168.1 | 0 | 1 | 256 | 1 | 256 | unknown [Zea mays] |
DDBJ | BAC79743.1 | 0 | 1 | 373 | 1 | 371 | putative alpha 3 glucosyltransferase [Oryza sativa Japonica Group] |
RefSeq | NP_001058960.1 | 0 | 1 | 351 | 109 | 468 | Os07g0164500 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001145139.1 | 0 | 1 | 373 | 1 | 373 | hypothetical protein LOC100278369 [Zea mays] |
RefSeq | XP_002305159.1 | 0 | 44 | 373 | 15 | 341 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
dolichyl-diphosphooligosaccharide biosynthesis | RXN-5470 | EC-2.4.1.267 | Dol-P-Glc:Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |