| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si036667m |
| Family | CE10 |
| Protein Properties | Length: 320 Molecular Weight: 34020.5 Isoelectric Point: 4.5336 |
| Chromosome | Chromosome/Scaffold: 9 Start: 22779270 End: 22780619 |
| Description | alpha/beta-Hydrolases superfamily protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 35 | 317 | 0 |
| ADAATGVVSKDVVIDDDSGIYVRLYLPDMAGTQANEDGPKLRVLVFLHGGGFITESAASPMYHNYVNSLAAAARVLVVSVNYRLAPEHRFPTGYEDSLRA LKWALSGGDPWLSRHGDLGRVFLAGDSAGGNIIHNVAMMAAAAGDGGGVAARIEGAVLLHAAFAGKEPVAGESVETAEMMDTLWGVICREAAEDGLDDPR INPLAAAAPSLRGLPFERLLVVEADGDFFRGRGRAYYEAVVASGWGGEVEWFETMGKEHVFFLLDPGCPEAVALMARLVAFFA | |||
| Full Sequence |
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| Protein Sequence Length: 320 Download |
| MDPSSEVILD YPIFRIYKDH HVDRLVGTET VPAGADAATG VVSKDVVIDD DSGIYVRLYL 60 PDMAGTQANE DGPKLRVLVF LHGGGFITES AASPMYHNYV NSLAAAARVL VVSVNYRLAP 120 EHRFPTGYED SLRALKWALS GGDPWLSRHG DLGRVFLAGD SAGGNIIHNV AMMAAAAGDG 180 GGVAARIEGA VLLHAAFAGK EPVAGESVET AEMMDTLWGV ICREAAEDGL DDPRINPLAA 240 AAPSLRGLPF ERLLVVEADG DFFRGRGRAY YEAVVASGWG GEVEWFETMG KEHVFFLLDP 300 GCPEAVALMA RLVAFFAGN* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| PRK10162 | PRK10162 | 0.0002 | 56 | 166 | 116 | + acetyl esterase; Provisional |
| cd00312 | Esterase_lipase | 3.0e-5 | 55 | 168 | 128 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. |
| pfam00135 | COesterase | 2.0e-6 | 69 | 168 | 115 | + Carboxylesterase family. |
| COG0657 | Aes | 2.0e-20 | 56 | 317 | 265 | + Esterase/lipase [Lipid metabolism] |
| pfam07859 | Abhydrolase_3 | 3.0e-37 | 78 | 297 | 226 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACG31893.1 | 0 | 3 | 319 | 4 | 315 | gibberellin receptor GID1L2 [Zea mays] |
| RefSeq | NP_001140223.1 | 0 | 3 | 319 | 4 | 315 | hypothetical protein LOC100272258 [Zea mays] |
| RefSeq | NP_001141390.1 | 0 | 1 | 319 | 1 | 324 | hypothetical protein LOC100273481 [Zea mays] |
| RefSeq | NP_001148840.1 | 0 | 1 | 319 | 1 | 312 | gibberellin receptor GID1L2 [Zea mays] |
| RefSeq | NP_001152234.1 | 0 | 1 | 319 | 1 | 324 | gibberellin receptor GID1L2 [Zea mays] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3ed1_F | 3e-36 | 5 | 319 | 24 | 350 | A Chain A, E. Coli Gsp Amidase Cys59 Sulfenic Acid |
| PDB | 3ed1_E | 3e-36 | 5 | 319 | 24 | 350 | A Chain A, E. Coli Gsp Amidase Cys59 Sulfenic Acid |
| PDB | 3ed1_D | 3e-36 | 5 | 319 | 24 | 350 | A Chain A, E. Coli Gsp Amidase Cys59 Sulfenic Acid |
| PDB | 3ed1_C | 3e-36 | 5 | 319 | 24 | 350 | A Chain A, E. Coli Gsp Amidase Cys59 Sulfenic Acid |
| PDB | 3ed1_B | 3e-36 | 5 | 319 | 24 | 350 | A Chain A, E. Coli Gsp Amidase Cys59 Sulfenic Acid |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DV516369 | 291 | 3 | 291 | 0 |
| EE164195 | 275 | 5 | 277 | 0 |
| EE035112 | 268 | 3 | 268 | 0 |
| EB165963 | 262 | 3 | 262 | 0 |
| DV512881 | 263 | 3 | 263 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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