Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si038995m |
Family | AA3 |
Protein Properties | Length: 590 Molecular Weight: 64725.1 Isoelectric Point: 10.9096 |
Chromosome | Chromosome/Scaffold: 9 Start: 57852769 End: 57854921 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 45 | 581 | 0 |
APLVSYYNYIIVGGGTAGCPLAATLSEHSRVLLLERGGLPYGNRNVSSEYHFADALADTSPLSPAQRFVSEDGVVNARARVLGGGSCLNAGFYTRASSGY VGAAGWDHRLVNASYRWVERALVFRPGVPRWQCALREGLIEAGITPDNGYTLEHVPGTKIGGTIFDRRGRRHTAADFLRKAHPRRLTVFLHATGVANPVA YGVVFTDPVGVQHHVYLRRGGAKNEVILAAGTLGSPQLLMLSGVGPRLHLEKHGIRTVHDQPGVGQGVADNPMNSVFVPSPIPVAHSLVQVVGVTRFGSF IEGVSGSQFGIPLHGRGAARRAARNFGMFSPMTGQLGTVPPRERTPEAMRRAAEVMRRLDRRAFRGGFILEKILGPLSTGHIELRSTDAHANPAVTFNYF RDPRDVERCVRGIEAIQRVVRSRAFSRFTYANHTAMEAVFRRAAGTAYFPVNLLPRHPRDTRPLHQYCRETVMTIWHYHGGCHVGGVVDRDYRVIGVRGL RVIDSSTFKYSPGTNPQATVMMLGRYMGLRILKERWI |
Full Sequence |
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Protein Sequence Length: 590 Download |
MSAGHMSTAA LLILATVLGS FCINATASRE AQRYNFRFVR HARDAPLVSY YNYIIVGGGT 60 AGCPLAATLS EHSRVLLLER GGLPYGNRNV SSEYHFADAL ADTSPLSPAQ RFVSEDGVVN 120 ARARVLGGGS CLNAGFYTRA SSGYVGAAGW DHRLVNASYR WVERALVFRP GVPRWQCALR 180 EGLIEAGITP DNGYTLEHVP GTKIGGTIFD RRGRRHTAAD FLRKAHPRRL TVFLHATGVA 240 NPVAYGVVFT DPVGVQHHVY LRRGGAKNEV ILAAGTLGSP QLLMLSGVGP RLHLEKHGIR 300 TVHDQPGVGQ GVADNPMNSV FVPSPIPVAH SLVQVVGVTR FGSFIEGVSG SQFGIPLHGR 360 GAARRAARNF GMFSPMTGQL GTVPPRERTP EAMRRAAEVM RRLDRRAFRG GFILEKILGP 420 LSTGHIELRS TDAHANPAVT FNYFRDPRDV ERCVRGIEAI QRVVRSRAFS RFTYANHTAM 480 EAVFRRAAGT AYFPVNLLPR HPRDTRPLHQ YCRETVMTIW HYHGGCHVGG VVDRDYRVIG 540 VRGLRVIDSS TFKYSPGTNP QATVMMLGRY MGLRILKERW IRKGAEDKH* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK02106 | PRK02106 | 3.0e-10 | 420 | 576 | 166 | + choline dehydrogenase; Validated | ||
TIGR01810 | betA | 2.0e-22 | 52 | 315 | 313 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
PRK02106 | PRK02106 | 7.0e-32 | 51 | 314 | 318 | + choline dehydrogenase; Validated | ||
COG2303 | BetA | 4.0e-36 | 51 | 579 | 583 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 6 | 579 | 592 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAO15286.1 | 0 | 19 | 583 | 24 | 586 | Putative mandelonitrile lyase [Oryza sativa Japonica Group] |
GenBank | EAY79265.1 | 0 | 35 | 582 | 40 | 588 | hypothetical protein OsI_34381 [Oryza sativa Indica Group] |
GenBank | EAY88296.1 | 0 | 19 | 583 | 24 | 586 | hypothetical protein OsI_09753 [Oryza sativa Indica Group] |
RefSeq | XP_002467623.1 | 0 | 1 | 580 | 1 | 580 | hypothetical protein SORBIDRAFT_01g031110 [Sorghum bicolor] |
RefSeq | XP_002468629.1 | 0 | 1 | 589 | 1 | 602 | hypothetical protein SORBIDRAFT_01g049320 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ju2_B | 0 | 25 | 579 | 2 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 1ju2_A | 0 | 25 | 579 | 2 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_B | 0 | 25 | 579 | 2 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_A | 0 | 25 | 579 | 2 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdn_B | 0 | 25 | 579 | 2 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |