Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si039200m |
Family | GT47 |
Protein Properties | Length: 499 Molecular Weight: 56747.8 Isoelectric Point: 8.1342 |
Chromosome | Chromosome/Scaffold: 9 Start: 56357095 End: 56358591 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 97 | 439 | 0 |
CRGRYVYIHDLPPRFNADILANCAHWYPWHNMCGYLENGGLGEPVDNADGVFADKGWYATDHFGLDIIFHRRVQQYDCLTDDPSRAAAVFVPFYAGFDIV QHLWGVNSTAKEKDALSLDLVEWLTRRPEWRAMGGRDHFFLSGRTAYDHQRQPESDSEWGSKLLHLPAVQNMTVLFVEKLPWTDFDFAIPYPTYFHPAKD AQILEWQRRMRAMKRRWLFSFAGGARNDPYSIRHHLIRQCGSSSFCKLVQCRKNERNCLIPSTFMRVFQGTRFCLQPTGDTMTRRSAFDAIMAGCVPVFF HPDSAHTQYRWHLPEAHETYSVLIPEADVRAGNVSIEETLRRI |
Full Sequence |
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Protein Sequence Length: 499 Download |
MEKTGAHGGK RWLPRLLLLA ALSWLLMVYF HLAVFRAPLV SAPHASIVAV PSDGAEDGQR 60 FLLRQQQQLK KIGSTSVGAL HTAVAERRPR GGDDAACRGR YVYIHDLPPR FNADILANCA 120 HWYPWHNMCG YLENGGLGEP VDNADGVFAD KGWYATDHFG LDIIFHRRVQ QYDCLTDDPS 180 RAAAVFVPFY AGFDIVQHLW GVNSTAKEKD ALSLDLVEWL TRRPEWRAMG GRDHFFLSGR 240 TAYDHQRQPE SDSEWGSKLL HLPAVQNMTV LFVEKLPWTD FDFAIPYPTY FHPAKDAQIL 300 EWQRRMRAMK RRWLFSFAGG ARNDPYSIRH HLIRQCGSSS FCKLVQCRKN ERNCLIPSTF 360 MRVFQGTRFC LQPTGDTMTR RSAFDAIMAG CVPVFFHPDS AHTQYRWHLP EAHETYSVLI 420 PEADVRAGNV SIEETLRRIP PEVAERMTET VIGLIPRLVY ADPRSRLETL RDAVDVTVEA 480 IVARVNKLRE EMGGGSAQQ |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-71 | 96 | 439 | 360 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAO17348.1 | 0 | 1 | 497 | 1 | 498 | Hypothetical protein [Oryza sativa Japonica Group] |
GenBank | EAY88513.1 | 0 | 1 | 497 | 1 | 498 | hypothetical protein OsI_09986 [Oryza sativa Indica Group] |
RefSeq | NP_001048944.1 | 0 | 97 | 497 | 28 | 427 | Os03g0144500 [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_001147481.1 | 0 | 8 | 499 | 18 | 544 | xyloglucan galactosyltransferase KATAMARI 1 [Zea mays] |
RefSeq | XP_002468518.1 | 0 | 1 | 497 | 1 | 499 | hypothetical protein SORBIDRAFT_01g047280 [Sorghum bicolor] |