Basic Information | |
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Species | Setaria italica |
Cazyme ID | Si040002m |
Family | AA3 |
Protein Properties | Length: 584 Molecular Weight: 63460 Isoelectric Point: 7.9224 |
Chromosome | Chromosome/Scaffold: 9 Start: 40751644 End: 40753663 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 38 | 582 | 0 |
RRAQDAPLVSHYNYIIIGGGTAGCPLAATLSEHSRVLLLERGGLPYRNMSNQQHFTDALADTSPASPAQRFISEDGVVNARARVLGGGSCLNAGFYTRAS NDYVHAAGWDARLVNSSYRWVERALVFRPDVPPWQAALRDALLEAGVTPDNGFTFDHVTGTKIGGTIFDSSGQRHTAADFLRHARPGGLTVLLYATVSRI LFRQQEGAPYPVAYGVVFSDPLGVQHRVYLQDGGKNEVILSAGTLGSPQLLMLSGVGPQAHLEAHGVQVLVDQPMVGQGVADNPMNSVFIPSPVPVALSL VQVVGITRTGSFIEGVSGSEFGIPVSEGVRRLARNFGLFSPQLQTGQLGTLPPKQRTPEALQRAAEAMRRLDRRAFRGGFILEKILGPVSSGHIELRSTD PRANPAVTFNYFQEKEDLDRCVHGIETIERVIQSRAFANFTYANASVESIFTDSANFPVNLLPRHANDSRTPEQYCRDTVMTIWHYHGGCQVGAVVDDDY RVFGVQRLRVIDSSTFKYSPGTNPQATVMMLGRYMGVKIQAERWR |
Full Sequence |
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Protein Sequence Length: 584 Download |
MALGLASSAA LVLATILGSL CLVALSEDEQ LENLRFVRRA QDAPLVSHYN YIIIGGGTAG 60 CPLAATLSEH SRVLLLERGG LPYRNMSNQQ HFTDALADTS PASPAQRFIS EDGVVNARAR 120 VLGGGSCLNA GFYTRASNDY VHAAGWDARL VNSSYRWVER ALVFRPDVPP WQAALRDALL 180 EAGVTPDNGF TFDHVTGTKI GGTIFDSSGQ RHTAADFLRH ARPGGLTVLL YATVSRILFR 240 QQEGAPYPVA YGVVFSDPLG VQHRVYLQDG GKNEVILSAG TLGSPQLLML SGVGPQAHLE 300 AHGVQVLVDQ PMVGQGVADN PMNSVFIPSP VPVALSLVQV VGITRTGSFI EGVSGSEFGI 360 PVSEGVRRLA RNFGLFSPQL QTGQLGTLPP KQRTPEALQR AAEAMRRLDR RAFRGGFILE 420 KILGPVSSGH IELRSTDPRA NPAVTFNYFQ EKEDLDRCVH GIETIERVIQ SRAFANFTYA 480 NASVESIFTD SANFPVNLLP RHANDSRTPE QYCRDTVMTI WHYHGGCQVG AVVDDDYRVF 540 GVQRLRVIDS STFKYSPGTN PQATVMMLGR YMGVKIQAER WRK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK02106 | PRK02106 | 3.0e-15 | 425 | 569 | 152 | + choline dehydrogenase; Validated | ||
PRK02106 | PRK02106 | 5.0e-31 | 48 | 319 | 325 | + choline dehydrogenase; Validated | ||
TIGR01810 | betA | 2.0e-33 | 50 | 569 | 582 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 1.0e-45 | 48 | 570 | 569 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 33 | 580 | 561 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAF65820.1 | 0 | 33 | 583 | 40 | 589 | AF251031_1 putative mandelonitrile lyase [Oryza sativa] |
GenBank | ACN28873.1 | 0 | 86 | 583 | 1 | 496 | unknown [Zea mays] |
GenBank | EAY79265.1 | 0 | 33 | 583 | 40 | 588 | hypothetical protein OsI_34381 [Oryza sativa Indica Group] |
RefSeq | NP_001065107.1 | 0 | 27 | 583 | 32 | 586 | Os10g0524500 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002467623.1 | 0 | 1 | 583 | 1 | 582 | hypothetical protein SORBIDRAFT_01g031110 [Sorghum bicolor] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3red_L | 0 | 23 | 580 | 1 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_K | 0 | 23 | 580 | 1 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_J | 0 | 23 | 580 | 1 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_I | 0 | 23 | 580 | 1 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_H | 0 | 23 | 580 | 1 | 518 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |