| Basic Information | |
|---|---|
| Species | Thellungiella halophila |
| Cazyme ID | Thhalv10001932m |
| Family | GT47 |
| Protein Properties | Length: 616 Molecular Weight: 70003.7 Isoelectric Point: 7.1566 |
| Chromosome | Chromosome/Scaffold: 12 Start: 10641015 End: 10643516 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 149 | 488 | 0 |
| GKYIYVHDLPSRFNEDMLRDCKKLSLWTNMCKFTTNAGLGPPLENVEGVFSDEGWYATNQFAVDVIFSNRMKQYKCLTNDSSLAAAIFVPFYAGFDIARY LWGYNISTRDAASLELVDWLMKRPEWDIMKGKDHFLVAGRITWDFRRLSEEETDWGNKLLFLPAAKNMSMLVVESSPWNANDFGIPYPTYFHPAKDSEVF EWQERMRNLERKWLFSFAGAPRPDNPKSIRGQIINQCRSSKVGKLLECDFGESKCHAPSSIMQMFQGSLFCLQPQGDSYTRRSAFDSMLAGCIPVFFHPG SAYTQYTWHLPKNYTTYSVFIPEDDIRKRNMSIEERLLQI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 616 Download |
| MIPRVAMRRR SAEVAPTEPT EKGNGKNQTN RICLLVALSL FFWALLLYFH FVVIGSSSID 60 KQIQLQPSYA QSQPSSVSLR VDKFPLEPQA SPSKPPKEGL VTVDKPMLPP APVANSTSTF 120 EPPRIVEKQE FPFIRALKTV DNKSDPCGGK YIYVHDLPSR FNEDMLRDCK KLSLWTNMCK 180 FTTNAGLGPP LENVEGVFSD EGWYATNQFA VDVIFSNRMK QYKCLTNDSS LAAAIFVPFY 240 AGFDIARYLW GYNISTRDAA SLELVDWLMK RPEWDIMKGK DHFLVAGRIT WDFRRLSEEE 300 TDWGNKLLFL PAAKNMSMLV VESSPWNAND FGIPYPTYFH PAKDSEVFEW QERMRNLERK 360 WLFSFAGAPR PDNPKSIRGQ IINQCRSSKV GKLLECDFGE SKCHAPSSIM QMFQGSLFCL 420 QPQGDSYTRR SAFDSMLAGC IPVFFHPGSA YTQYTWHLPK NYTTYSVFIP EDDIRKRNMS 480 IEERLLQIPP EQVKVMRENV INLIPGLIYA DPRSELETLK DAFDVSVQAV IDKVTRLRKN 540 MIVGRTEYDN FVEENSWKYA LLEEGQREAG GHVWDPFFSK PKPGEDSSSD GSGGTTISAD 600 AAKNSWKSEQ RDKTQ* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 5.0e-68 | 146 | 488 | 358 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD21751.1 | 0 | 21 | 615 | 2 | 600 | unknown protein [Arabidopsis thaliana] |
| DDBJ | BAE98519.1 | 0 | 1 | 615 | 1 | 619 | hypothetical protein [Arabidopsis thaliana] |
| DDBJ | BAH19963.1 | 0 | 146 | 615 | 1 | 470 | AT2G20370 [Arabidopsis thaliana] |
| RefSeq | NP_179627.2 | 0 | 1 | 615 | 1 | 619 | MUR3 (MURUS 3); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002301846.1 | 0 | 21 | 614 | 2 | 585 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
